Caging and uncaging genetics

Tom J Little; Nick Colegrave

doi:10.1371/journal.pbio.1002525

Caging and uncaging genetics

Tom J Little, Nick Colegrave

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments where genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse population that mirrors the wild? What is the best design for studying genetic variation? When should we consider it at all? The right experimental approach depends on what you want to know.

Original language	English
Journal	PLoS Biology
Volume	14
Issue number	7
DOIs	https://doi.org/10.1371/journal.pbio.1002525
Publication status	Published - 26 Jul 2016

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10.1371/journal.pbio.1002525

Caging and uncaging geneticsAccepted author manuscript, 612 KB
journal.pbio.1002525
Copyright: © 2016 Little, Colegrave. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Final published version, 819 KBLicence: Creative Commons: Attribution (CC-BY)

1 Finished

The genetics and evolution of maternal effects on parasite resistance
Little, T.
NERC
15/02/12 → 31/12/15
Project: Research

Thomas Little
- School of Biological Sciences - Personal Chair in Evolutionary Biology
Person: Academic: Research Active

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Caging and uncaging genetics

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The genetics and evolution of maternal effects on parasite resistance

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Thomas Little

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