Can pharmaceutical use during pregnancy affect the reproductive health of the offspring?

Care is required when administrating pharmaceuticals to pregnant women, bearing in mind not only the mother-to-be’s health but also that of the unborn offspring. Until now, studies of fetal outcomes have primarily focused on avoiding major effects, but some outcomes could become apparent only later. This perspective discusses whether fetal exposure to pharmaceuticals administered to a pregnant woman could affect the developing reproductive system, potentially resulting in fertility problems, even with consequences for subsequent generations. Different circumstances in which pregnant women can be administered pharmaceuticals are examined, some where there is a necessity for treatment, but others that may be dispensable.