Cancer Immunosurveillance: role of patrolling monocytes.

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Classical inflammatory monocytes and their derivative macrophages promote tumor metastasis whereas CD8 T and NK cells restrict tumor growth. In a recent paper published in Science, Hanna and colleagues demonstrate that another monocyte population, nonclassical patrolling monocytes, is enriched in the microvasculature of tumor-challenged lung and reduces tumor metastasis by recruiting NK cells.

Original languageEnglish
JournalCell Research
Publication statusPublished - 4 Dec 2015


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