Capillary and Venous Lactate Agreement: A pilot prospective observational study

Deepankar Datta; Julia Grahamslaw; Alasdair James Gray; Catriona Graham

doi:10.1136/emermed-2016-206109

Capillary and Venous Lactate Agreement: A pilot prospective observational study

Deepankar Datta^*, Julia Grahamslaw, Alasdair James Gray, Catriona Graham

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Background Blood lactate is a marker of patient illness severity. Capillary lactate (CAP-LACT) measurement can potentially improve patient screening; however, it has poor evidence of clinical utility. Aim We aimed to investigate agreement between CAP-LACT and peripheral venous lactate (PV-LACT). Methods We performed a prospective observational pilot study of 99 patients requiring lactate measurement. Paired CAP-LACT and PV-LACT was recorded. Agreement was determined by Bland-Altman analysis. Results Bias was 0.2 mmol/L, with 95% limits of agreement from -1.9 to 2.3. Conclusions CAP-LACT has poor agreement with PV-LACT. Further research is needed to improve its potential clinical utility.

Original language	English
Pages (from-to)	195-197
Number of pages	3
Journal	Emergency Medicine Journal
Volume	34
Issue number	3
Early online date	21 Sept 2016
DOIs	https://doi.org/10.1136/emermed-2016-206109
Publication status	Published - Mar 2017

Keywords / Materials (for Non-textual outputs)

Adolescent
Adult
Blood Gas Analysis
Capillaries
Female
Humans
Lactic Acid
Male
Middle Aged
Pilot Projects
Prospective Studies
Sensitivity and Specificity
United Kingdom
Veins
Journal Article
Observational Study

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10.1136/emermed-2016-206109

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@article{e7e28049ea254bef8059df2d03f635db,

title = "Capillary and Venous Lactate Agreement: A pilot prospective observational study",

abstract = "Background Blood lactate is a marker of patient illness severity. Capillary lactate (CAP-LACT) measurement can potentially improve patient screening; however, it has poor evidence of clinical utility. Aim We aimed to investigate agreement between CAP-LACT and peripheral venous lactate (PV-LACT). Methods We performed a prospective observational pilot study of 99 patients requiring lactate measurement. Paired CAP-LACT and PV-LACT was recorded. Agreement was determined by Bland-Altman analysis. Results Bias was 0.2 mmol/L, with 95% limits of agreement from -1.9 to 2.3. Conclusions CAP-LACT has poor agreement with PV-LACT. Further research is needed to improve its potential clinical utility.",

keywords = "Adolescent, Adult, Blood Gas Analysis, Capillaries, Female, Humans, Lactic Acid, Male, Middle Aged, Pilot Projects, Prospective Studies, Sensitivity and Specificity, United Kingdom, Veins, Journal Article, Observational Study",

author = "Deepankar Datta and Julia Grahamslaw and Gray, {Alasdair James} and Catriona Graham",

note = "Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.",

year = "2017",

month = mar,

doi = "10.1136/emermed-2016-206109",

language = "English",

volume = "34",

pages = "195--197",

journal = "Emergency Medicine Journal",

issn = "1472-0205",

publisher = "BMJ Publishing Group",

number = "3",

}

TY - JOUR

T1 - Capillary and Venous Lactate Agreement

T2 - A pilot prospective observational study

AU - Datta, Deepankar

AU - Grahamslaw, Julia

AU - Gray, Alasdair James

AU - Graham, Catriona

N1 - Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

PY - 2017/3

Y1 - 2017/3

N2 - Background Blood lactate is a marker of patient illness severity. Capillary lactate (CAP-LACT) measurement can potentially improve patient screening; however, it has poor evidence of clinical utility. Aim We aimed to investigate agreement between CAP-LACT and peripheral venous lactate (PV-LACT). Methods We performed a prospective observational pilot study of 99 patients requiring lactate measurement. Paired CAP-LACT and PV-LACT was recorded. Agreement was determined by Bland-Altman analysis. Results Bias was 0.2 mmol/L, with 95% limits of agreement from -1.9 to 2.3. Conclusions CAP-LACT has poor agreement with PV-LACT. Further research is needed to improve its potential clinical utility.

AB - Background Blood lactate is a marker of patient illness severity. Capillary lactate (CAP-LACT) measurement can potentially improve patient screening; however, it has poor evidence of clinical utility. Aim We aimed to investigate agreement between CAP-LACT and peripheral venous lactate (PV-LACT). Methods We performed a prospective observational pilot study of 99 patients requiring lactate measurement. Paired CAP-LACT and PV-LACT was recorded. Agreement was determined by Bland-Altman analysis. Results Bias was 0.2 mmol/L, with 95% limits of agreement from -1.9 to 2.3. Conclusions CAP-LACT has poor agreement with PV-LACT. Further research is needed to improve its potential clinical utility.

KW - Adolescent

KW - Adult

KW - Blood Gas Analysis

KW - Capillaries

KW - Female

KW - Humans

KW - Lactic Acid

KW - Male

KW - Middle Aged

KW - Pilot Projects

KW - Prospective Studies

KW - Sensitivity and Specificity

KW - United Kingdom

KW - Veins

KW - Journal Article

KW - Observational Study

UR - http://www.scopus.com/inward/record.url?scp=84988648659&partnerID=8YFLogxK

U2 - 10.1136/emermed-2016-206109

DO - 10.1136/emermed-2016-206109

M3 - Article

C2 - 27655882

AN - SCOPUS:84988648659

SN - 1472-0205

VL - 34

SP - 195

EP - 197

JO - Emergency Medicine Journal

JF - Emergency Medicine Journal

IS - 3

ER -

Capillary and Venous Lactate Agreement: A pilot prospective observational study

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