Abstract
Integrins are a family of transmembrane proteins that allow communication between the extracellular matrix and the interior of cells. Chondrocytes, cells of articular cartilage, express integrins and these molecules appear to have a variety of roles including mechanotransduction. Integrins are known to associate with a number of accessory molecules such as CD147 that may act to regulate their activity. The purpose of this study was to investigate the expression of CD147 in normal and osteoarthritis human articular cartilage and identify potential roles in mechanical signalling.
| Original language | English |
|---|---|
| Pages (from-to) | 153-8 |
| Number of pages | 6 |
| Journal | Iranian biomedical journal |
| Volume | 12 |
| Issue number | 3 |
| Publication status | Published - 2008 |