Cell Biology of Ureter Development

Adrian S. Woolf, Jamie A. Davies

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

The mammalian ureter contains two main cell types: a multilayered water-tight epithelium called the urothelium, surrounded by smooth muscle layers that, by generating proximal to distal peristaltic waves, pump urine from the renal pelvis toward the urinary bladder. Here, we review the cellular mechanisms involved in the development of these tissues, and the molecules that control the process. We consider the relevance of these biologic findings for understanding the pathogenesis of human ureter malformations. J Am Soc Nephrol 24: 19-25, 2013. doi: 10.1681/ASN.2012020127

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Original languageEnglish
Pages (from-to)19-25
Number of pages7
JournalJournal of the American Society of Nephrology
Volume24
Issue number1
DOIs
Publication statusPublished - Jan 2013

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