Cellular orchestrators of renal fibrosis

B. Conway; J. Hughes

doi:10.1093/qjmed/hcr235

Cellular orchestrators of renal fibrosis

B. Conway, J. Hughes^*

^*Corresponding author for this work

Research output: Contribution to journal › Literature review › peer-review

Abstract

Renal fibrosis is a key determinant of the progression of many renal diseases and represents a final common pathway that adversely affects outcome. The evolution of renal fibrosis is complicated and involves many cellular and molecular mediators. In this review we will outline the key players in the fibrotic response of the injured kidney and discuss emerging research in the field.

Original language	English
Pages (from-to)	611-615
Number of pages	5
Journal	QJM: An International Journal of Medicine
Volume	105
Issue number	7
DOIs	https://doi.org/10.1093/qjmed/hcr235
Publication status	Published - Jul 2012

Keywords / Materials (for Non-textual outputs)

FIBROBLASTS
REPAIR
TARGET
COLLAGEN
PERICYTE
PROGRESSION
EMT
MACROPHAGES
CHRONIC KIDNEY-DISEASE

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10.1093/qjmed/hcr235

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title = "Cellular orchestrators of renal fibrosis",

abstract = "Renal fibrosis is a key determinant of the progression of many renal diseases and represents a final common pathway that adversely affects outcome. The evolution of renal fibrosis is complicated and involves many cellular and molecular mediators. In this review we will outline the key players in the fibrotic response of the injured kidney and discuss emerging research in the field.",

keywords = "FIBROBLASTS, REPAIR, TARGET, COLLAGEN, PERICYTE, PROGRESSION, EMT, MACROPHAGES, CHRONIC KIDNEY-DISEASE",

author = "B. Conway and J. Hughes",

year = "2012",

month = jul,

doi = "10.1093/qjmed/hcr235",

language = "English",

volume = "105",

pages = "611--615",

journal = "QJM: An International Journal of Medicine",

issn = "1460-2725",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Cellular orchestrators of renal fibrosis

AU - Conway, B.

AU - Hughes, J.

PY - 2012/7

Y1 - 2012/7

N2 - Renal fibrosis is a key determinant of the progression of many renal diseases and represents a final common pathway that adversely affects outcome. The evolution of renal fibrosis is complicated and involves many cellular and molecular mediators. In this review we will outline the key players in the fibrotic response of the injured kidney and discuss emerging research in the field.

AB - Renal fibrosis is a key determinant of the progression of many renal diseases and represents a final common pathway that adversely affects outcome. The evolution of renal fibrosis is complicated and involves many cellular and molecular mediators. In this review we will outline the key players in the fibrotic response of the injured kidney and discuss emerging research in the field.

KW - FIBROBLASTS

KW - REPAIR

KW - TARGET

KW - COLLAGEN

KW - PERICYTE

KW - PROGRESSION

KW - EMT

KW - MACROPHAGES

KW - CHRONIC KIDNEY-DISEASE

U2 - 10.1093/qjmed/hcr235

DO - 10.1093/qjmed/hcr235

M3 - Literature review

SN - 1460-2725

VL - 105

SP - 611

EP - 615

JO - QJM: An International Journal of Medicine

JF - QJM: An International Journal of Medicine

IS - 7

ER -

Cellular orchestrators of renal fibrosis

Abstract

Keywords / Materials (for Non-textual outputs)

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