Cellular orchestrators of renal fibrosis

B. Conway, J. Hughes*

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review

Abstract / Description of output

Renal fibrosis is a key determinant of the progression of many renal diseases and represents a final common pathway that adversely affects outcome. The evolution of renal fibrosis is complicated and involves many cellular and molecular mediators. In this review we will outline the key players in the fibrotic response of the injured kidney and discuss emerging research in the field.

Original languageEnglish
Pages (from-to)611-615
Number of pages5
JournalQJM: An International Journal of Medicine
Volume105
Issue number7
DOIs
Publication statusPublished - Jul 2012

Keywords / Materials (for Non-textual outputs)

  • FIBROBLASTS
  • REPAIR
  • TARGET
  • COLLAGEN
  • PERICYTE
  • PROGRESSION
  • EMT
  • MACROPHAGES
  • CHRONIC KIDNEY-DISEASE

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