Cerebral amyloid angiopathy in traumatic brain injury: association with apolipoprotein E genotype

P D Leclercq, L S Murray, C Smith, D I Graham, J A R Nicoll, S M Gentleman

Research output: Contribution to journalArticlepeer-review

Abstract

In view of the association of the apolipoprotein E (APOE) epsilon 4 allele with poor outcome after traumatic brain injury we determined the frequency of cerebral amyloid angiopathy (CAA) and the extent of haemorrhagic pathology in relation to APOE genotype in an autopsy series of 88 head injured cases.
Original languageEnglish
Pages (from-to)229-33
Number of pages5
JournalJournal of Neurology, Neurosurgery & Psychiatry
Volume76
Issue number2
DOIs
Publication statusPublished - Feb 2005

Keywords

  • Adolescent
  • Adult
  • Aged
  • Apolipoproteins E
  • Autopsy
  • Brain Injuries
  • Cerebral Amyloid Angiopathy
  • Child
  • Child, Preschool
  • Female
  • Genetic Predisposition to Disease
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Intracranial Hemorrhages
  • Male
  • Middle Aged
  • Prognosis
  • Risk Factors
  • Severity of Illness Index

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