TY - JOUR
T1 - Cessation of smoking trial in the emergency department (CoSTED)
T2 - protocol for a multicentre randomised controlled trial
AU - Notley, Caitlin
AU - Clark, Lucy
AU - Belderson, Pippa
AU - Ward, Emma
AU - Clark, Allan B
AU - Parrott, Steve
AU - Agrawal, Sanjay
AU - Bloom, Ben M
AU - Boyle, Adrian A
AU - Morris, Geraint
AU - Gray, Alasdair
AU - Coats, Tim
AU - Man, Mei-see
AU - Bauld, Linda
AU - Holland, Richard
AU - Pope, Ian
N1 - Funding Information:
This study is funded by the National Institute for Health Research (NIHR) HTA programme Tobacco Cessation, Control and Harm Reduction (project reference 129438).
Publisher Copyright:
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.
PY - 2023/1/18
Y1 - 2023/1/18
N2 - INTRODUCTION: Attendees of emergency departments (EDs) have a higher than expected prevalence of smoking. ED attendance may be a good opportunity to prompt positive behaviour change, even for smokers not currently motivated to quit. This study aims to determine whether an opportunist smoking cessation intervention delivered in the ED can help daily smokers attending the ED quit smoking and is cost-effective.METHODS AND ANALYSIS: A two-arm pragmatic, multicentred, parallel-group, individually randomised, controlled superiority trial with an internal pilot, economic evaluation and mixed methods process evaluation. The trial will compare ED-based brief smoking cessation advice, including provision of an e-cigarette and referral to local stop smoking services (intervention) with the provision of contact details for local stop smoking services (control). Target sample size is 972, recruiting across 6 National Health Service EDs in England and Scotland. Outcomes will be collected at 1, 3 and 6 months. The primary outcome at 6 months is carbon monoxide verified continuous smoking abstinence.ETHICS AND DISSEMINATION: The trial was approved by the South Central-Oxford B Research Committee (21/SC/0288). Dissemination will include the publication of outcomes, and the process and economic evaluations in peer-reviewed journals. The findings will also be appropriately disseminated to relevant practice, policy and patient representative groups.TRIAL REGISTRATION NUMBER: NCT04854616; protocol V.4.2.
AB - INTRODUCTION: Attendees of emergency departments (EDs) have a higher than expected prevalence of smoking. ED attendance may be a good opportunity to prompt positive behaviour change, even for smokers not currently motivated to quit. This study aims to determine whether an opportunist smoking cessation intervention delivered in the ED can help daily smokers attending the ED quit smoking and is cost-effective.METHODS AND ANALYSIS: A two-arm pragmatic, multicentred, parallel-group, individually randomised, controlled superiority trial with an internal pilot, economic evaluation and mixed methods process evaluation. The trial will compare ED-based brief smoking cessation advice, including provision of an e-cigarette and referral to local stop smoking services (intervention) with the provision of contact details for local stop smoking services (control). Target sample size is 972, recruiting across 6 National Health Service EDs in England and Scotland. Outcomes will be collected at 1, 3 and 6 months. The primary outcome at 6 months is carbon monoxide verified continuous smoking abstinence.ETHICS AND DISSEMINATION: The trial was approved by the South Central-Oxford B Research Committee (21/SC/0288). Dissemination will include the publication of outcomes, and the process and economic evaluations in peer-reviewed journals. The findings will also be appropriately disseminated to relevant practice, policy and patient representative groups.TRIAL REGISTRATION NUMBER: NCT04854616; protocol V.4.2.
KW - Electronic Nicotine Delivery Systems
KW - England
KW - Humans
KW - Multicenter Studies as Topic
KW - Randomized Controlled Trials as Topic
KW - Smoking Cessation/methods
KW - Smoking/epidemiology
KW - State Medicine
U2 - 10.1136/bmjopen-2022-064585
DO - 10.1136/bmjopen-2022-064585
M3 - Article
C2 - 36657751
SN - 2044-6055
VL - 13
SP - e064585
JO - BMJ Open
JF - BMJ Open
IS - 1
ER -