Cetaceans evolution: insights from the genome sequences of common minke whales

Jung Youn Park; Yong-Rock An; Naohisa Kanda; Chul-Min An; Hye Suck An; Jung-Ha Kang; Eun Mi Kim; Du-Hae An; Hojin Jung; Myunghee Joung; Myung Hum Park; Sook Hee Yoon; Bo-Young Lee; Taeheon Lee; Kyu-Won Kim; Won Cheoul Park; Dong Hyun Shin; Young Sub Lee; Jaemin Kim; Woori Kwak; Hyeon Jeong Kim; Young-Jun Kwon; Sunjin Moon; Yuseob Kim; David W. Burt; Seoae Cho; Heebal Kim

doi:10.1186/s12864-015-1213-1

Cetaceans evolution: insights from the genome sequences of common minke whales

Jung Youn Park
, Yong-Rock An
, Naohisa Kanda
, Chul-Min An
, Hye Suck An
, Jung-Ha Kang
, Eun Mi Kim
, Du-Hae An
, Hojin Jung
, Myunghee Joung
, Myung Hum Park
, Sook Hee Yoon
, Bo-Young Lee
, Taeheon Lee
, Kyu-Won Kim
, Won Cheoul Park
, Dong Hyun Shin
, Young Sub Lee
, Jaemin Kim
, Woori Kwak

Hyeon Jeong Kim, Young-Jun Kwon, Sunjin Moon, Yuseob Kim, David W. Burt, Seoae Cho, Heebal Kim^*

^*Corresponding author for this work

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Whales have captivated the human imagination for millennia. These incredible cetaceans are the only mammals that have adapted to life in the open oceans and have been a source of human food, fuel and tools around the globe. The transition from land to water has led to various aquatic specializations related to hairless skin and ability to regulate their body temperature in cold water.

Results: We present four common minke whale (Balaenoptera acutorostrata) genomes with depth of x13 similar to x17 coverage and perform resequencing technology without a reference sequence. Our results indicated the time to the most recent common ancestors of common minke whales to be about 2.3574 (95% HPD, 1.1521 - 3.9212) million years ago. Further, we found that genes associated with epilation and tooth-development showed signatures of positive selection, supporting the morphological uniqueness of whales.

Conclusions: This whole-genome sequencing offers a chance to better understand the evolutionary journey of one of the largest mammals on earth.

Original language	English
Article number	13
Number of pages	8
Journal	BMC Genomics
Volume	16
DOIs	https://doi.org/10.1186/s12864-015-1213-1
Publication status	Published - 22 Jan 2015

Keywords / Materials (for Non-textual outputs)

Cetaceans
Common minke whale
Positive selection
Genome
MAXIMUM-LIKELIHOOD
NEUROPEPTIDE-Y
TISSUE INTERACTIONS
ALIGNMENT
ADAPTATIONS
PHYLOGENIES
CELLS
GENE
ASPARTYLGLUCOSAMINURIA
HOMEOSTASIS

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10.1186/s12864-015-1213-1

Cetaceans evolution insights from the genome sequences of common minke whales
© 2015 Park et al.; licensee Biomed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Final published version, 939 KBLicence: Creative Commons: Attribution (CC-BY)

http://www.biomedcentral.com/1471-2164/16/13

Cite this

Park, J. Y., An, Y.-R., Kanda, N., An, C.-M., An, H. S., Kang, J.-H., Kim, E. M., An, D.-H., Jung, H., Joung, M., Park, M. H., Yoon, S. H., Lee, B.-Y., Lee, T., Kim, K.-W., Park, W. C., Shin, D. H., Lee, Y. S., Kim, J., ... Kim, H. (2015). Cetaceans evolution: insights from the genome sequences of common minke whales. BMC Genomics, 16, Article 13. https://doi.org/10.1186/s12864-015-1213-1

@article{93efe39146cc45239cd34c634ac3cf83,

title = "Cetaceans evolution: insights from the genome sequences of common minke whales",

abstract = "Background: Whales have captivated the human imagination for millennia. These incredible cetaceans are the only mammals that have adapted to life in the open oceans and have been a source of human food, fuel and tools around the globe. The transition from land to water has led to various aquatic specializations related to hairless skin and ability to regulate their body temperature in cold water.Results: We present four common minke whale (Balaenoptera acutorostrata) genomes with depth of x13 similar to x17 coverage and perform resequencing technology without a reference sequence. Our results indicated the time to the most recent common ancestors of common minke whales to be about 2.3574 (95\% HPD, 1.1521 - 3.9212) million years ago. Further, we found that genes associated with epilation and tooth-development showed signatures of positive selection, supporting the morphological uniqueness of whales.Conclusions: This whole-genome sequencing offers a chance to better understand the evolutionary journey of one of the largest mammals on earth.",

keywords = "Cetaceans, Common minke whale, Positive selection, Genome, MAXIMUM-LIKELIHOOD, NEUROPEPTIDE-Y, TISSUE INTERACTIONS, ALIGNMENT, ADAPTATIONS, PHYLOGENIES, CELLS, GENE, ASPARTYLGLUCOSAMINURIA, HOMEOSTASIS",

author = "Park, \{Jung Youn\} and Yong-Rock An and Naohisa Kanda and Chul-Min An and An, \{Hye Suck\} and Jung-Ha Kang and Kim, \{Eun Mi\} and Du-Hae An and Hojin Jung and Myunghee Joung and Park, \{Myung Hum\} and Yoon, \{Sook Hee\} and Bo-Young Lee and Taeheon Lee and Kyu-Won Kim and Park, \{Won Cheoul\} and Shin, \{Dong Hyun\} and Lee, \{Young Sub\} and Jaemin Kim and Woori Kwak and Kim, \{Hyeon Jeong\} and Young-Jun Kwon and Sunjin Moon and Yuseob Kim and Burt, \{David W.\} and Seoae Cho and Heebal Kim",

year = "2015",

month = jan,

day = "22",

doi = "10.1186/s12864-015-1213-1",

language = "English",

volume = "16",

journal = "BMC Genomics",

issn = "1471-2164",

publisher = "BioMed Central",

}

Park, JY, An, Y-R, Kanda, N, An, C-M, An, HS, Kang, J-H, Kim, EM, An, D-H, Jung, H, Joung, M, Park, MH, Yoon, SH, Lee, B-Y, Lee, T, Kim, K-W, Park, WC, Shin, DH, Lee, YS, Kim, J, Kwak, W, Kim, HJ, Kwon, Y-J, Moon, S, Kim, Y, Burt, DW, Cho, S & Kim, H 2015, 'Cetaceans evolution: insights from the genome sequences of common minke whales', BMC Genomics, vol. 16, 13. https://doi.org/10.1186/s12864-015-1213-1

TY - JOUR

T1 - Cetaceans evolution

T2 - insights from the genome sequences of common minke whales

AU - Park, Jung Youn

AU - An, Yong-Rock

AU - Kanda, Naohisa

AU - An, Chul-Min

AU - An, Hye Suck

AU - Kang, Jung-Ha

AU - Kim, Eun Mi

AU - An, Du-Hae

AU - Jung, Hojin

AU - Joung, Myunghee

AU - Park, Myung Hum

AU - Yoon, Sook Hee

AU - Lee, Bo-Young

AU - Lee, Taeheon

AU - Kim, Kyu-Won

AU - Park, Won Cheoul

AU - Shin, Dong Hyun

AU - Lee, Young Sub

AU - Kim, Jaemin

AU - Kwak, Woori

AU - Kim, Hyeon Jeong

AU - Kwon, Young-Jun

AU - Moon, Sunjin

AU - Kim, Yuseob

AU - Burt, David W.

AU - Cho, Seoae

AU - Kim, Heebal

PY - 2015/1/22

Y1 - 2015/1/22

N2 - Background: Whales have captivated the human imagination for millennia. These incredible cetaceans are the only mammals that have adapted to life in the open oceans and have been a source of human food, fuel and tools around the globe. The transition from land to water has led to various aquatic specializations related to hairless skin and ability to regulate their body temperature in cold water.Results: We present four common minke whale (Balaenoptera acutorostrata) genomes with depth of x13 similar to x17 coverage and perform resequencing technology without a reference sequence. Our results indicated the time to the most recent common ancestors of common minke whales to be about 2.3574 (95% HPD, 1.1521 - 3.9212) million years ago. Further, we found that genes associated with epilation and tooth-development showed signatures of positive selection, supporting the morphological uniqueness of whales.Conclusions: This whole-genome sequencing offers a chance to better understand the evolutionary journey of one of the largest mammals on earth.

AB - Background: Whales have captivated the human imagination for millennia. These incredible cetaceans are the only mammals that have adapted to life in the open oceans and have been a source of human food, fuel and tools around the globe. The transition from land to water has led to various aquatic specializations related to hairless skin and ability to regulate their body temperature in cold water.Results: We present four common minke whale (Balaenoptera acutorostrata) genomes with depth of x13 similar to x17 coverage and perform resequencing technology without a reference sequence. Our results indicated the time to the most recent common ancestors of common minke whales to be about 2.3574 (95% HPD, 1.1521 - 3.9212) million years ago. Further, we found that genes associated with epilation and tooth-development showed signatures of positive selection, supporting the morphological uniqueness of whales.Conclusions: This whole-genome sequencing offers a chance to better understand the evolutionary journey of one of the largest mammals on earth.

KW - Cetaceans

KW - Common minke whale

KW - Positive selection

KW - Genome

KW - MAXIMUM-LIKELIHOOD

KW - NEUROPEPTIDE-Y

KW - TISSUE INTERACTIONS

KW - ALIGNMENT

KW - ADAPTATIONS

KW - PHYLOGENIES

KW - CELLS

KW - GENE

KW - ASPARTYLGLUCOSAMINURIA

KW - HOMEOSTASIS

U2 - 10.1186/s12864-015-1213-1

DO - 10.1186/s12864-015-1213-1

M3 - Article

SN - 1471-2164

VL - 16

JO - BMC Genomics

JF - BMC Genomics

M1 - 13

ER -

Cetaceans evolution: insights from the genome sequences of common minke whales

Abstract

Keywords / Materials (for Non-textual outputs)

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