Abstract / Description of output
The role of the hippocampus during memory consolidation is not fully understood, with human and animal experiments producing conflicting conclusions. In particular, human lesion studies tend to indicate that the hippocampus gradually becomes independent from memory over years, whilst animal studies suggest that this can happen over days. Tallman et al. (this issue) used fMRI to investigate activity and functional connectivity in the brain at four different time points following memory encoding. Their findings include a decrease in functional connectivity between the hippocampus and parahippocampal cortex with memory age, which supports the system consolidation theory, but also argues against the reduced involvement of the hippocampus over time. This study sheds new light on the neurobiology of memory.
Original language | English |
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Pages (from-to) | 141-143 |
Number of pages | 3 |
Journal | Cognitive Neuroscience |
Volume | 13 |
Issue number | 3-4 |
Early online date | 13 Jun 2022 |
DOIs | |
Publication status | Published - Jul 2022 |
Keywords / Materials (for Non-textual outputs)
- Animals
- Humans
- Memory Consolidation
- Hippocampus/diagnostic imaging
- Brain Mapping
- Magnetic Resonance Imaging
- Brain/diagnostic imaging