Changes in continuous glucose monitoring metrics and predictors of improvement 12 months after conversion from Freestyle Libre to Freestyle Libre 2

Roland H. Stimson; Anna R. Dover; Mark W. J. Strachan; Rohana J. Wright; Shareen Forbes; Fraser W. Gibb

doi:10.1111/dme.15130

Changes in continuous glucose monitoring metrics and predictors of improvement 12 months after conversion from Freestyle Libre to Freestyle Libre 2

Roland H. Stimson, Anna R. Dover, Mark W. J. Strachan, Rohana J. Wright, Shareen Forbes, Fraser W. Gibb

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Aims
We sought to assess whether conversion from Freestyle Libre to Freestyle Libre 2 (with low and high glucose alert functions) was associated with improved glucose metrics.

Research Design and methods
A prospective observational study to assess changes in CGM metrics in 672 adults with type 1 diabetes when converting to Freestyle Libre 2. Secondary outcomes included predictors of reduction in time below range (TBR) and increase in time in range (TIR).

Results
TBR fell by a median of 1.0% (IQR -2.7 – 0.3, p
Conclusions
Conversion to Freestyle Libre 2 was associated with significant improvements in low glucose metrics. Alert function users were more likely to see improvements across all CGM metrics. Challenges remain in encouraging alert use, helping users set optimal alert thresholds and optimizing response to alerts.

Original language	English
Journal	Diabetic Medicine
Early online date	8 May 2023
DOIs	https://doi.org/10.1111/dme.15130
Publication status	E-pub ahead of print - 8 May 2023

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10.1111/dme.15130Licence: Creative Commons: Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND)

Libre 2 DM v2clean versionAccepted author manuscript, 63.1 KBLicence: Creative Commons: Attribution (CC-BY)

https://onlinelibrary.wiley.com/doi/10.1111/dme.15130

Cite this

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title = "Changes in continuous glucose monitoring metrics and predictors of improvement 12 months after conversion from Freestyle Libre to Freestyle Libre 2",

abstract = "AimsWe sought to assess whether conversion from Freestyle Libre to Freestyle Libre 2 (with low and high glucose alert functions) was associated with improved glucose metrics. Research Design and methodsA prospective observational study to assess changes in CGM metrics in 672 adults with type 1 diabetes when converting to Freestyle Libre 2. Secondary outcomes included predictors of reduction in time below range (TBR) and increase in time in range (TIR). ResultsTBR fell by a median of 1.0% (IQR -2.7 – 0.3, p ConclusionsConversion to Freestyle Libre 2 was associated with significant improvements in low glucose metrics. Alert function users were more likely to see improvements across all CGM metrics. Challenges remain in encouraging alert use, helping users set optimal alert thresholds and optimizing response to alerts.",

author = "Stimson, {Roland H.} and Dover, {Anna R.} and Strachan, {Mark W. J.} and Wright, {Rohana J.} and Shareen Forbes and Gibb, {Fraser W.}",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.",

year = "2023",

month = may,

day = "8",

doi = "10.1111/dme.15130",

language = "English",

journal = "Diabetic Medicine",

issn = "0742-3071",

publisher = "Wiley-Blackwell",

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TY - JOUR

T1 - Changes in continuous glucose monitoring metrics and predictors of improvement 12 months after conversion from Freestyle Libre to Freestyle Libre 2

AU - Stimson, Roland H.

AU - Dover, Anna R.

AU - Strachan, Mark W. J.

AU - Wright, Rohana J.

AU - Forbes, Shareen

AU - Gibb, Fraser W.

PY - 2023/5/8

Y1 - 2023/5/8

N2 - AimsWe sought to assess whether conversion from Freestyle Libre to Freestyle Libre 2 (with low and high glucose alert functions) was associated with improved glucose metrics. Research Design and methodsA prospective observational study to assess changes in CGM metrics in 672 adults with type 1 diabetes when converting to Freestyle Libre 2. Secondary outcomes included predictors of reduction in time below range (TBR) and increase in time in range (TIR). ResultsTBR fell by a median of 1.0% (IQR -2.7 – 0.3, p ConclusionsConversion to Freestyle Libre 2 was associated with significant improvements in low glucose metrics. Alert function users were more likely to see improvements across all CGM metrics. Challenges remain in encouraging alert use, helping users set optimal alert thresholds and optimizing response to alerts.

AB - AimsWe sought to assess whether conversion from Freestyle Libre to Freestyle Libre 2 (with low and high glucose alert functions) was associated with improved glucose metrics. Research Design and methodsA prospective observational study to assess changes in CGM metrics in 672 adults with type 1 diabetes when converting to Freestyle Libre 2. Secondary outcomes included predictors of reduction in time below range (TBR) and increase in time in range (TIR). ResultsTBR fell by a median of 1.0% (IQR -2.7 – 0.3, p ConclusionsConversion to Freestyle Libre 2 was associated with significant improvements in low glucose metrics. Alert function users were more likely to see improvements across all CGM metrics. Challenges remain in encouraging alert use, helping users set optimal alert thresholds and optimizing response to alerts.

U2 - 10.1111/dme.15130

DO - 10.1111/dme.15130

M3 - Article

SN - 0742-3071

JO - Diabetic Medicine

JF - Diabetic Medicine

ER -

Changes in continuous glucose monitoring metrics and predictors of improvement 12 months after conversion from Freestyle Libre to Freestyle Libre 2

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