Changes in continuous glucose monitoring metrics and predictors of improvement 12 months after conversion from Freestyle Libre to Freestyle Libre 2

Roland H. Stimson, Anna R. Dover, Mark W. J. Strachan, Rohana J. Wright, Shareen Forbes, Fraser W. Gibb

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Aims
We sought to assess whether conversion from Freestyle Libre to Freestyle Libre 2 (with low and high glucose alert functions) was associated with improved glucose metrics.

Research Design and methods
A prospective observational study to assess changes in CGM metrics in 672 adults with type 1 diabetes when converting to Freestyle Libre 2. Secondary outcomes included predictors of reduction in time below range (TBR) and increase in time in range (TIR).

Results
TBR fell by a median of 1.0% (IQR -2.7 – 0.3, p
Conclusions
Conversion to Freestyle Libre 2 was associated with significant improvements in low glucose metrics. Alert function users were more likely to see improvements across all CGM metrics. Challenges remain in encouraging alert use, helping users set optimal alert thresholds and optimizing response to alerts.
Original languageEnglish
JournalDiabetic Medicine
Early online date8 May 2023
DOIs
Publication statusE-pub ahead of print - 8 May 2023

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