Characterisation of a novel murine intestinal serine protease, DISP

C J Shaw-Smith, A J Coffey, M Leversha, T C Freeman, D R Bentley, J R Walters

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

A putative novel murine serine protease, DISP, was identified by cDNA indexing and shown to be expressed primarily in distal gut. FISH analysis showed it to be localised to mouse chromosome 17A3. A possible human homologue for DISP has been identified. DISP is a novel member of clan SA/family S1 of the serine proteases, at present of unknown function.
Original languageEnglish
Pages (from-to)131-6
Number of pages6
JournalBBA - Bioenergetics
Issue number1-2
Publication statusPublished - 31 Jan 2000

Keywords / Materials (for Non-textual outputs)

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • DNA, Complementary
  • Electrophoresis, Agar Gel
  • Epithelial Cells
  • Gene Expression
  • Ileum
  • Intestine, Small
  • Mice
  • Mice, Inbred C57BL
  • Molecular Sequence Data
  • RNA, Messenger
  • Reverse Transcriptase Polymerase Chain Reaction
  • Serine Endopeptidases


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