Characterization and Control of the Run-and-Tumble Dynamics of Escherichia Coli

Christina Kurzthaler; Yongfeng Zhao; Nan Zhou; Jana Schwarz-Linek; Clemence Devailly; Jochen Arlt; Jian-Dong Huang; Wilson C. K. Poon; Thomas Franosch; Julien Tailleur; Vincent A. Martinez

doi:10.1103/PhysRevLett.132.038302

Characterization and Control of the Run-and-Tumble Dynamics of Escherichia Coli

Christina Kurzthaler^*, Yongfeng Zhao, Nan Zhou, Jana Schwarz-Linek, Clemence Devailly, Jochen Arlt, Jian-Dong Huang, Wilson C. K. Poon, Thomas Franosch, Julien Tailleur, Vincent A. Martinez

^*Corresponding author for this work

School of Physics and Astronomy

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

We characterize the full spatiotemporal gait of populations of swimming Escherichia coli using renewal processes to analyze the measurements of intermediate scattering functions. This allows us to demonstrate quantitatively how the persistence length of an engineered strain can be controlled
by a chemical inducer and to report a controlled transition from perpetual tumbling to smooth swimming. For wild-type E. coli, we measure simultaneously the microscopic motility parameters and the large-scale effective diffusivity, hence quantitatively bridging for the first time small-scale directed swimming and macroscopic diffusion.

Original language	English
Article number	038302
Pages (from-to)	1-7
Number of pages	7
Journal	Physical Review Letters
Volume	132
Issue number	3
DOIs	https://doi.org/10.1103/PhysRevLett.132.038302
Publication status	Published - 19 Jan 2024

Keywords / Materials (for Non-textual outputs)

cond-mat.soft
physics.bio-ph

Access to Document

10.1103/PhysRevLett.132.038302

Kurzthaler et al. - 2024 - Characterization and Control of the Run-and-Tumble
Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. Open access publication funded by the Max Planck Society.
Final published version, 792 KBLicence: Creative Commons: Attribution (CC-BY)

https://arxiv.org/abs/2212.11222Licence: Creative Commons: Attribution (CC-BY)

PHYSAPS: The Physics of Active Particle Suspensions
Poon, W.
EU government bodies
1/02/14 → 31/01/20
Project: Research

Cite this

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title = "Characterization and Control of the Run-and-Tumble Dynamics of Escherichia Coli",

abstract = "We characterize the full spatiotemporal gait of populations of swimming Escherichia coli using renewal processes to analyze the measurements of intermediate scattering functions. This allows us to demonstrate quantitatively how the persistence length of an engineered strain can be controlledby a chemical inducer and to report a controlled transition from perpetual tumbling to smooth swimming. For wild-type E. coli, we measure simultaneously the microscopic motility parameters and the large-scale effective diffusivity, hence quantitatively bridging for the first time small-scale directed swimming and macroscopic diffusion.",

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author = "Christina Kurzthaler and Yongfeng Zhao and Nan Zhou and Jana Schwarz-Linek and Clemence Devailly and Jochen Arlt and Jian-Dong Huang and Poon, {Wilson C. K.} and Thomas Franosch and Julien Tailleur and Martinez, {Vincent A.}",

note = "Funding Information: This work was supported by the Austrian Science Fund (FWF) via P35580-N and the Erwin Schr{\"o}dinger fellowship (J4321-N27), the European Research Council Grant No. AdG-340877-PHYSAPS, the ANR grant Bactterns, the Shenzhen Peacock Team Project (KQTD2015033117210153), and the National Key Research and Development Program of China (2021YFA0910700). Publisher Copyright: {\textcopyright} 2024 authors. Published by the American Physical Society. Published by the American Physical Society under the terms of the {"}https://creativecommons.org/licenses/by/4.0/{"}Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Open access publication funded by the Max Planck Society.",

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AU - Kurzthaler, Christina

AU - Zhao, Yongfeng

AU - Zhou, Nan

AU - Schwarz-Linek, Jana

AU - Devailly, Clemence

AU - Arlt, Jochen

AU - Huang, Jian-Dong

AU - Poon, Wilson C. K.

AU - Franosch, Thomas

AU - Tailleur, Julien

AU - Martinez, Vincent A.

N1 - Funding Information: This work was supported by the Austrian Science Fund (FWF) via P35580-N and the Erwin Schrödinger fellowship (J4321-N27), the European Research Council Grant No. AdG-340877-PHYSAPS, the ANR grant Bactterns, the Shenzhen Peacock Team Project (KQTD2015033117210153), and the National Key Research and Development Program of China (2021YFA0910700). Publisher Copyright: © 2024 authors. Published by the American Physical Society. Published by the American Physical Society under the terms of the "https://creativecommons.org/licenses/by/4.0/"Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Open access publication funded by the Max Planck Society.

PY - 2024/1/19

Y1 - 2024/1/19

N2 - We characterize the full spatiotemporal gait of populations of swimming Escherichia coli using renewal processes to analyze the measurements of intermediate scattering functions. This allows us to demonstrate quantitatively how the persistence length of an engineered strain can be controlledby a chemical inducer and to report a controlled transition from perpetual tumbling to smooth swimming. For wild-type E. coli, we measure simultaneously the microscopic motility parameters and the large-scale effective diffusivity, hence quantitatively bridging for the first time small-scale directed swimming and macroscopic diffusion.

AB - We characterize the full spatiotemporal gait of populations of swimming Escherichia coli using renewal processes to analyze the measurements of intermediate scattering functions. This allows us to demonstrate quantitatively how the persistence length of an engineered strain can be controlledby a chemical inducer and to report a controlled transition from perpetual tumbling to smooth swimming. For wild-type E. coli, we measure simultaneously the microscopic motility parameters and the large-scale effective diffusivity, hence quantitatively bridging for the first time small-scale directed swimming and macroscopic diffusion.

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KW - physics.bio-ph

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Characterization and Control of the Run-and-Tumble Dynamics of Escherichia Coli

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Keywords / Materials (for Non-textual outputs)

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Projects

PHYSAPS: The Physics of Active Particle Suspensions

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