Checkpoint signalling: Mad2 conformers and signal propagation

Kevin G Hardwick

doi:10.1016/j.cub.2005.02.008

Checkpoint signalling: Mad2 conformers and signal propagation

Kevin G Hardwick

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

The spindle checkpoint protein Mad2 has a tendency to form multimers and adopts at least two structural conformations. New work highlights the importance of the Mad2-Mad2 interaction, and suggests how spindle checkpoint signals are propagated away from kinetochores.

Original language	English
Pages (from-to)	R122-4
Journal	Current biology : CB
Volume	15
Issue number	4
DOIs	https://doi.org/10.1016/j.cub.2005.02.008
Publication status	Published - 2005

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10.1016/j.cub.2005.02.008

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title = "Checkpoint signalling: Mad2 conformers and signal propagation",

abstract = "The spindle checkpoint protein Mad2 has a tendency to form multimers and adopts at least two structural conformations. New work highlights the importance of the Mad2-Mad2 interaction, and suggests how spindle checkpoint signals are propagated away from kinetochores.",

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year = "2005",

doi = "10.1016/j.cub.2005.02.008",

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T2 - Mad2 conformers and signal propagation

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Y1 - 2005

N2 - The spindle checkpoint protein Mad2 has a tendency to form multimers and adopts at least two structural conformations. New work highlights the importance of the Mad2-Mad2 interaction, and suggests how spindle checkpoint signals are propagated away from kinetochores.

AB - The spindle checkpoint protein Mad2 has a tendency to form multimers and adopts at least two structural conformations. New work highlights the importance of the Mad2-Mad2 interaction, and suggests how spindle checkpoint signals are propagated away from kinetochores.

U2 - 10.1016/j.cub.2005.02.008

DO - 10.1016/j.cub.2005.02.008

M3 - Article

C2 - 15723780

SN - 0960-9822

VL - 15

SP - R122-4

JO - Current biology : CB

JF - Current biology : CB

IS - 4

ER -

Checkpoint signalling: Mad2 conformers and signal propagation

Abstract / Description of output

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