Chloride channel 2 gene (Clc2) maps to chromosome 16 of the mouse, extending a region of conserved synteny with human chromosome 3q

A Lengeling, M Gronemeier, M Ronsiek, A Thiemann, T J Jentsch, H Jockusch

Research output: Contribution to journalArticlepeer-review

Abstract

The Clc2 gene of the mouse codes for the ubiquitously expressed chloride channel ClC-2, a member of a family of at least seven voltage gated chloride channels, some of which are implicated in hereditary diseases. Using a mouse interspecies back-cross panel, we have mapped Clc2 to Chr 16, proximal to the somatostatin gene Smst, extending a region of documented conserved synteny to human Chr 3q.
Original languageEnglish
Pages (from-to)175-8
Number of pages4
JournalGenetics Research
Volume66
Issue number2
Publication statusPublished - Oct 1995

Keywords

  • Animals
  • Chloride Channels
  • Chromosome Mapping
  • Chromosomes, Human, Pair 3
  • Humans
  • Mice
  • Mice, Inbred C57BL

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