Chromosomal localization of nine porcine genes encoding transcription factors involved in adipogenesis

I Szczerbal, A Chmurzynska

Research output: Contribution to journalArticlepeer-review

Abstract

Chromosomal localization of nine porcine genes encoding transcription factors involved in adipogenesis was determined. BAC clones harboring sequences of selected genes CEBPA (SSC6q12), CEBPB (SSC17q23), CEBPD (SSC4q15), CEBPG (SSC6q12), PPARG (SSC13q24), SREBF1 (SSC10q17), DDIT3 (SSC12q15), GATA2 (SSC13q24 -->q31) and GATA3 (SSC5p12) were mapped by FISH. The positions of these genes in the human and pig genomes were compared. A potential role of the genes encoding adipogenesis factors as candidate genes for fatness traits as well as obesity-related phenotypes is discussed.
Original languageEnglish
Pages (from-to)50-4
Number of pages5
JournalCytogenetic and Genome Research
Volume121
Issue number1
DOIs
Publication statusPublished - 2008

Keywords

  • Adipogenesis
  • Animals
  • Base Sequence
  • CCAAT-Enhancer-Binding Proteins
  • Chromosomes, Artificial, Bacterial
  • Cytogenetics
  • DNA Primers
  • GATA2 Transcription Factor
  • In Situ Hybridization, Fluorescence
  • PPAR gamma
  • Swine
  • Transcription Factors

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