Chronic kidney disease risk in African and Caribbean populations with HIV

UK CHIC Study

Research output: Contribution to journalArticlepeer-review

Abstract

We conducted an observational cohort study of end-stage kidney disease (ESKD) in >7000 African and Caribbean people with HIV in the UK. Using Poisson regression and East Africans as the reference group, the adjusted incidence rate ratio (95% confidence interval) of ESKD was 3.14 (1.26-7.84) in Southern Africans, 6.35 (2.53-15.96) in West Africans, and 5.26 (1.91-14.43) in Caribbeans. Higher CD4 cell count and suppressed HIV replication were associated with reduced risk of ESKD. The risk of ESKD varied among HIV-positive people of African heritage, with the highest rates observed in those of West African descent.

Original languageEnglish
Pages (from-to)1767-1772
Number of pages6
JournalJournal of Infectious Diseases
Volume218
Issue number11
DOIs
Publication statusPublished - 6 Jul 2018

Keywords

  • Africa
  • Caribbean
  • Chronic kidney disease
  • HIV
  • Incidence

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