Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: a multicentre cohort study

Xiaolong Qi, Yanna Liu, Jitao Wang, Jonathan Fallowfield, Jianwen Wang, Xinyu Li, Jindong Shi, Hongqiu Pan, Shengqiang Zou, Hongguang Zhang, Zhenhuai Chen, Fujian Li, Yan Luo, Mei Mei, Huiling Liu, Zhengyan Wang, Jinlin Li, Hua Yang, Huihua Xiang, Xiaodan LiTao Liu, Ming-hua Zheng, Chuan Liu, Yifei Huang, Dan Xu, Xiaoguo Li, Ning Kang, Qing He, Ye Gu, Guo Zhang, Chuxiao Shao, Dengxiang Liu, Lin Zhang, Xun Li, Norifumi Kawada, Zicheng Jiang, Fengmei Wang, Bin Xiong, Tetsuo Takehara, Don C Rockey

Research output: Contribution to journalLetterpeer-review

Abstract

In this study we provide the first report of the characteristics, comorbidities,
laboratory and x-ray findings, and clinical outcomes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients with pre-existing liver cirrhosis. The cause of death in most patients was respiratory failure rather than progression of liver disease. Lower numbers of blood lymphocytes and platelets, and higher bilirubin levels might represent indicators of poor outcome in this patient population.





Original languageEnglish
Pages (from-to)gutjnl-2020-321666
JournalGut
Early online date20 May 2020
DOIs
Publication statusE-pub ahead of print - 20 May 2020

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