Clinical effects of isoflurane and sevoflurane in lambs

Enzo Vettorato; Gudrun Schoeffmann; John G Burke; Alastair J N Gibson; Eddie R Clutton

doi:10.1111/j.1467-2995.2012.00718.x

Clinical effects of isoflurane and sevoflurane in lambs

Enzo Vettorato, Gudrun Schoeffmann, John G Burke, Alastair J N Gibson, Eddie R Clutton

Research output: Contribution to journal › Article › peer-review

Abstract

Objective To compare isoflurane and sevoflurane in lambs undergoing prolonged anaesthesia for spinal surgery. Study design Prospective randomised clinical study. Animals Eighteen Scottish blackface lambs 3-6 weeks of age and weighing 10-17 kg. Methods After intramuscular medetomidine, anaesthesia was induced and maintained with either isoflurane (group I) or sevoflurane (group S) delivered in oxygen. Meloxicam, morphine, a constant rate infusion of ketamine and atracurium were given intravenously (IV) during surgery. Lungs were ventilated to maintain normocapnia. with peak inspiratory pressures of 20-25 cmH(2) O. Ephedrine or dextran 40% was administered when mean arterial pressure (MAP) was 1 minute), reunion with the ewe, and the number of MAP treatments were recorded. Statistical analysis utilised anova, Mann-Whitney, t-test or Pearson's correlation test as relevant. p

Original language	English
Pages (from-to)	495-502
Number of pages	8
Journal	Veterinary Anaesthesia and Analgesia
Volume	39
Issue number	5
DOIs	https://doi.org/10.1111/j.1467-2995.2012.00718.x
Publication status	Published - 2012

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10.1111/j.1467-2995.2012.00718.x

http://onlinelibrary.wiley.com/doi/10.1111/j.1467-2995.2012.00718.x/abstract

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@article{27f6b28d82e14550a252a47c07402a42,

title = "Clinical effects of isoflurane and sevoflurane in lambs",

abstract = "Objective To compare isoflurane and sevoflurane in lambs undergoing prolonged anaesthesia for spinal surgery. Study design Prospective randomised clinical study. Animals Eighteen Scottish blackface lambs 3-6 weeks of age and weighing 10-17 kg. Methods After intramuscular medetomidine, anaesthesia was induced and maintained with either isoflurane (group I) or sevoflurane (group S) delivered in oxygen. Meloxicam, morphine, a constant rate infusion of ketamine and atracurium were given intravenously (IV) during surgery. Lungs were ventilated to maintain normocapnia. with peak inspiratory pressures of 20-25 cmH(2) O. Ephedrine or dextran 40% was administered when mean arterial pressure (MAP) was 1 minute), reunion with the ewe, and the number of MAP treatments were recorded. Statistical analysis utilised anova, Mann-Whitney, t-test or Pearson's correlation test as relevant. p ",

author = "Enzo Vettorato and Gudrun Schoeffmann and Burke, {John G} and Gibson, {Alastair J N} and Clutton, {Eddie R}",

note = "{\textcopyright} 2012 The Authors. Veterinary Anaesthesia and Analgesia. {\textcopyright} 2012 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesiologists.",

year = "2012",

doi = "10.1111/j.1467-2995.2012.00718.x",

language = "English",

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pages = "495--502",

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T1 - Clinical effects of isoflurane and sevoflurane in lambs

AU - Vettorato, Enzo

AU - Schoeffmann, Gudrun

AU - Burke, John G

AU - Gibson, Alastair J N

AU - Clutton, Eddie R

PY - 2012

Y1 - 2012

N2 - Objective To compare isoflurane and sevoflurane in lambs undergoing prolonged anaesthesia for spinal surgery. Study design Prospective randomised clinical study. Animals Eighteen Scottish blackface lambs 3-6 weeks of age and weighing 10-17 kg. Methods After intramuscular medetomidine, anaesthesia was induced and maintained with either isoflurane (group I) or sevoflurane (group S) delivered in oxygen. Meloxicam, morphine, a constant rate infusion of ketamine and atracurium were given intravenously (IV) during surgery. Lungs were ventilated to maintain normocapnia. with peak inspiratory pressures of 20-25 cmH(2) O. Ephedrine or dextran 40% was administered when mean arterial pressure (MAP) was 1 minute), reunion with the ewe, and the number of MAP treatments were recorded. Statistical analysis utilised anova, Mann-Whitney, t-test or Pearson's correlation test as relevant. p

AB - Objective To compare isoflurane and sevoflurane in lambs undergoing prolonged anaesthesia for spinal surgery. Study design Prospective randomised clinical study. Animals Eighteen Scottish blackface lambs 3-6 weeks of age and weighing 10-17 kg. Methods After intramuscular medetomidine, anaesthesia was induced and maintained with either isoflurane (group I) or sevoflurane (group S) delivered in oxygen. Meloxicam, morphine, a constant rate infusion of ketamine and atracurium were given intravenously (IV) during surgery. Lungs were ventilated to maintain normocapnia. with peak inspiratory pressures of 20-25 cmH(2) O. Ephedrine or dextran 40% was administered when mean arterial pressure (MAP) was 1 minute), reunion with the ewe, and the number of MAP treatments were recorded. Statistical analysis utilised anova, Mann-Whitney, t-test or Pearson's correlation test as relevant. p

U2 - 10.1111/j.1467-2995.2012.00718.x

DO - 10.1111/j.1467-2995.2012.00718.x

M3 - Article

C2 - 22524433

SN - 1467-2995

VL - 39

SP - 495

EP - 502

JO - Veterinary Anaesthesia and Analgesia

JF - Veterinary Anaesthesia and Analgesia

IS - 5

ER -

Clinical effects of isoflurane and sevoflurane in lambs

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