Background: Canine idiopathic eosinophilic lung disease (ELD) is sparsely documented in the literature. Methods: Clinical presentation and outcome of dogs diagnosed with ELD(eosinophilic bronchitis or eosinophilic bronchopneumonia) were reviewed. Subgroups were made based on chronicity of clinical signs and findings of thoracic imaging: NCI (no changes in thoracic imaging), BRON (bronchial/peribronchial pattern), INT (Bronchointerstitial/Interstitial/alveolar). Results: Seventy cases were included. There were more young to adult, crossbreed and female dogs. Compared to the other two groups NCI dogs showed lower BALF eosinophilic pleocytosis and absence of circulating eosinophilia, bronchiectasis or death due to respiratory disease.All dogs responded clinically to corticosteroids. Median treatment duration was 4 months. Remission (no clinical signs after treatment discontinuation for >1 month) and long-term remission (>6 months) was achieved in 60%, and 51% of patients respectively. Relapse occurred in 26% of cases after remission but was rare (3%) after long- term remission. The 1,2, and 4-year survival to death due to respiratory disease was 98%, 97% and 91% respectively. Conclusion: Prognosis and initial clinical response for ELD was generally good although achievement of long-term remission was only seen in 51% of dogs. Different outcomes based on chronicity of signs, corticosteroid dose, thoracic imaging abnormalities and other clinical variables were not appreciated.
- Eosinophilic bronchopneumopathy
- Eosinophilic bronchitis