Abstract
Understanding variation in genome structure is essential to understand phenotypic differences within populations and the evolutionary history of species. A promising form of this structural variation is copy number variation (CNV). CNVs can be generated by different recombination mechanisms, such as non-allelic homologous recombination, that rely on specific characteristics of the genome architecture. These structural variants can therefore be more abundant at particular genes ultimately leading to variation in phenotypes under selection. Detailed characterization of CNVs therefore can reveal evolutionary footprints of selection and provide insight in their contribution to phenotypic variation in wild populations.
Original language | English |
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Article number | 195 |
Journal | BMC Genomics |
Volume | 19 |
Issue number | 1 |
DOIs | |
Publication status | Published - 13 Mar 2018 |
Externally published | Yes |
Keywords / Materials (for Non-textual outputs)
- genetic variation
- duplication
- inheritance
- parus major
- recombination