Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study

Generation Scotland

Research output: Contribution to journalArticlepeer-review

Abstract

Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences.
Original languageEnglish
Pages (from-to)91-96
Number of pages6
JournalBehavior Genetics
Volume44
Issue number2
DOIs
Publication statusPublished - Mar 2014

Keywords

  • Height
  • Intelligence
  • Molecular genetics
  • Genetic correlation
  • Generation Scotland
  • SCOTTISH FAMILY HEALTH
  • HERITABILITY
  • METAANALYSIS
  • ASSOCIATION
  • PLEIOTROPY
  • CHILDHOOD
  • DISEASE
  • SAMPLES
  • COHORT

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