Comparable efficacy of a topical 0.0584% hydrocortisone aceponate spray and oral ciclosporin in treating canine atopic dermatitis

Tim J Nuttall, Neil A McEwan, Emmanuel Bensignor, Luisa Cornegliani, Christine Löwenstein, Christophe A Rème

Research output: Contribution to journalArticlepeer-review

Abstract

This study compared the efficacy of a 0.0584% hydrocortisone aceponate (HCA) spray (Cortavance(®); Virbac SA) and ciclosporin (Atopica(®); Novartis Animal Health) in canine atopic dermatitis in a single-blind randomized controlled trial. Dogs received HCA (two sprays/100 cm(2); n=24) or ciclosporin (5 mg/kg; n=21). Canine Atopic Dermatitis Extent and Severity Index (CADESI)-03, pruritus (visual analog scale with grade descriptors) and owner scores (5-point scales) were recorded every 28 days for 84 days. Intention-to-treat data were analysed. CADESI-03 and pruritus significantly decreased over time (P
Original languageEnglish
Pages (from-to)4-10, e1-2
JournalVeterinary Dermatology
Volume23
Issue number1
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Administration, Oral
  • Administration, Topical
  • Aerosols
  • Animals
  • Cyclosporine
  • Dermatitis, Atopic
  • Dermatologic Agents
  • Dog Diseases
  • Dogs
  • Female
  • Hydrocortisone
  • Male
  • Single-Blind Method
  • Treatment Outcome

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