Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

Aspasia Angelakopoulou; Tina Shah; Reecha Sofat; Sonia Shah; Diane J Berry; Jackie Cooper; Jutta Palmen; Ioanna Tzoulaki; Andrew Wong; Barbara J Jefferis; Nikolas Maniatis; Fotios Drenos; Bruna Gigante; Rebecca Hardy; Ross C Laxton; Karin Leander; Anna Motterle; Iain A Simpson; Liam Smeeth; Andy Thomson; Claudio Verzilli; Diana Kuh; Helen Ireland; John Deanfield; Mark Caulfield; Chris Wallace; Nilesh Samani; Patricia B Munroe; Mark Lathrop; F Gerry R Fowkes; Michael Marmot; Peter H Whincup; John C Whittaker; Ulf de Faire; Mika Kivimaki; Meena Kumari; Elina Hypponen; Chris Power; Steve E Humphries; Philippa J Talmud; Jackie Price; Richard W Morris; Shu Ye; Juan P Casas; Aroon D Hingorani

doi:10.1093/eurheartj/ehr225

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

Aspasia Angelakopoulou, Tina Shah, Reecha Sofat, Sonia Shah, Diane J Berry, Jackie Cooper, Jutta Palmen, Ioanna Tzoulaki, Andrew Wong, Barbara J Jefferis, Nikolas Maniatis, Fotios Drenos, Bruna Gigante, Rebecca Hardy, Ross C Laxton, Karin Leander, Anna Motterle, Iain A Simpson, Liam Smeeth, Andy ThomsonClaudio Verzilli, Diana Kuh, Helen Ireland, John Deanfield, Mark Caulfield, Chris Wallace, Nilesh Samani, Patricia B Munroe, Mark Lathrop, F Gerry R Fowkes, Michael Marmot, Peter H Whincup, John C Whittaker, Ulf de Faire, Mika Kivimaki, Meena Kumari, Elina Hypponen, Chris Power, Steve E Humphries, Philippa J Talmud, Jackie Price, Richard W Morris, Shu Ye, Juan P Casas, Aroon D Hingorani

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Abstract / Description of output

To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association study-derived lipid-associated SNPs with other risk factors and CHD events.

Original language	English
Pages (from-to)	393-407
Number of pages	15
Journal	European Heart Journal
Volume	33
Issue number	3
DOIs	https://doi.org/10.1093/eurheartj/ehr225
Publication status	Published - 2012

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10.1093/eurheartj/ehr225

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease
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Angelakopoulou, A., Shah, T., Sofat, R., Shah, S., Berry, D. J., Cooper, J., Palmen, J., Tzoulaki, I., Wong, A., Jefferis, B. J., Maniatis, N., Drenos, F., Gigante, B., Hardy, R., Laxton, R. C., Leander, K., Motterle, A., Simpson, I. A., Smeeth, L., ... Hingorani, A. D. (2012). Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. European Heart Journal, 33(3), 393-407. https://doi.org/10.1093/eurheartj/ehr225

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title = "Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration",

abstract = "To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association study-derived lipid-associated SNPs with other risk factors and CHD events.",

author = "Aspasia Angelakopoulou and Tina Shah and Reecha Sofat and Sonia Shah and Berry, {Diane J} and Jackie Cooper and Jutta Palmen and Ioanna Tzoulaki and Andrew Wong and Jefferis, {Barbara J} and Nikolas Maniatis and Fotios Drenos and Bruna Gigante and Rebecca Hardy and Laxton, {Ross C} and Karin Leander and Anna Motterle and Simpson, {Iain A} and Liam Smeeth and Andy Thomson and Claudio Verzilli and Diana Kuh and Helen Ireland and John Deanfield and Mark Caulfield and Chris Wallace and Nilesh Samani and Munroe, {Patricia B} and Mark Lathrop and Fowkes, {F Gerry R} and Michael Marmot and Whincup, {Peter H} and Whittaker, {John C} and {de Faire}, Ulf and Mika Kivimaki and Meena Kumari and Elina Hypponen and Chris Power and Humphries, {Steve E} and Talmud, {Philippa J} and Jackie Price and Morris, {Richard W} and Shu Ye and Casas, {Juan P} and Hingorani, {Aroon D}",

year = "2012",

doi = "10.1093/eurheartj/ehr225",

language = "English",

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pages = "393--407",

journal = "European Heart Journal",

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Angelakopoulou, A, Shah, T, Sofat, R, Shah, S, Berry, DJ, Cooper, J, Palmen, J, Tzoulaki, I, Wong, A, Jefferis, BJ, Maniatis, N, Drenos, F, Gigante, B, Hardy, R, Laxton, RC, Leander, K, Motterle, A, Simpson, IA, Smeeth, L, Thomson, A, Verzilli, C, Kuh, D, Ireland, H, Deanfield, J, Caulfield, M, Wallace, C, Samani, N, Munroe, PB, Lathrop, M, Fowkes, FGR, Marmot, M, Whincup, PH, Whittaker, JC, de Faire, U, Kivimaki, M, Kumari, M, Hypponen, E, Power, C, Humphries, SE, Talmud, PJ, Price, J, Morris, RW, Ye, S, Casas, JP & Hingorani, AD 2012, 'Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration', European Heart Journal, vol. 33, no. 3, pp. 393-407. https://doi.org/10.1093/eurheartj/ehr225

TY - JOUR

T1 - Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease

T2 - Cardiovascular Biomarker Genetics Collaboration

AU - Angelakopoulou, Aspasia

AU - Shah, Tina

AU - Sofat, Reecha

AU - Shah, Sonia

AU - Berry, Diane J

AU - Cooper, Jackie

AU - Palmen, Jutta

AU - Tzoulaki, Ioanna

AU - Wong, Andrew

AU - Jefferis, Barbara J

AU - Maniatis, Nikolas

AU - Drenos, Fotios

AU - Gigante, Bruna

AU - Hardy, Rebecca

AU - Laxton, Ross C

AU - Leander, Karin

AU - Motterle, Anna

AU - Simpson, Iain A

AU - Smeeth, Liam

AU - Thomson, Andy

AU - Verzilli, Claudio

AU - Kuh, Diana

AU - Ireland, Helen

AU - Deanfield, John

AU - Caulfield, Mark

AU - Wallace, Chris

AU - Samani, Nilesh

AU - Munroe, Patricia B

AU - Lathrop, Mark

AU - Fowkes, F Gerry R

AU - Marmot, Michael

AU - Whincup, Peter H

AU - Whittaker, John C

AU - de Faire, Ulf

AU - Kivimaki, Mika

AU - Kumari, Meena

AU - Hypponen, Elina

AU - Power, Chris

AU - Humphries, Steve E

AU - Talmud, Philippa J

AU - Price, Jackie

AU - Morris, Richard W

AU - Ye, Shu

AU - Casas, Juan P

AU - Hingorani, Aroon D

PY - 2012

Y1 - 2012

N2 - To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association study-derived lipid-associated SNPs with other risk factors and CHD events.

AB - To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association study-derived lipid-associated SNPs with other risk factors and CHD events.

U2 - 10.1093/eurheartj/ehr225

DO - 10.1093/eurheartj/ehr225

M3 - Article

C2 - 21804106

SN - 1522-9645

VL - 33

SP - 393

EP - 407

JO - European Heart Journal

JF - European Heart Journal

IS - 3

ER -

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

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