Projects per year
Abstract
The 'transiently expressed in neural precursors' (TENP) gene product is a member of the bacterial/permeability-increasing (BPI) family of antimicrobial proteins but was first identified as having a role in an early neurological event occurring in post-mitotic cells. However, recent characterisation of the egg white proteome has shown that TENP is an important egg component constituting ~0.1-0.5% of the total protein and suggesting it is expressed in the adult oviduct. In this study we confirmed quantitatively that the expression of TENP is largely confined to the tubular glands of the magnum of the oviduct, where egg white synthesis occurs, with around 10,000 times more expression than in the embryo where TENP was first identified. TENP expression is significantly increased with the administration of oestrogen or progesterone (P
| Original language | English |
|---|---|
| Pages (from-to) | 99-108 |
| Journal | Gene |
| Volume | 538 |
| Issue number | 1 |
| Early online date | 10 Jan 2014 |
| DOIs | |
| Publication status | Published - 10 Jan 2014 |
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Dive into the research topics of 'Comparative biology and expression of TENP, an egg protein related to the bacterial permeability-increasing family of proteins'. Together they form a unique fingerprint.Projects
- 2 Finished
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Control of development and reproductive traits
Burdon, T. (Principal Investigator), Argyle, D. (Co-investigator), Ashworth, C. (Co-investigator), Beard, P. (Co-investigator), Brunton, P. (Co-investigator), Burt, D. (Co-investigator), Clinton, M. (Co-investigator), Dunn, I. (Co-investigator), Farquharson, C. (Co-investigator), Headon, D. (Co-investigator), Hocking, P. (Co-investigator), Hohenstein, P. (Co-investigator), Hume, D. (Co-investigator), Jackson, I. (Co-investigator), McColl, B. (Co-investigator), McGrew, M. (Co-investigator), McLachlan, G. (Co-investigator), Sang, H. (Co-investigator), Summers, K. (Co-investigator) & Whitelaw, B. (Co-investigator)
1/04/12 → 31/03/17
Project: Research
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The identification and development of novel antimicrobial peptides to control enteric disease in poultry and pigs: studentship natasha whenham
Dunn, I. (Principal Investigator)
UK industry, commerce and public corporations
6/09/10 → 28/02/15
Project: Research