Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies

Suzanne G St Rose; Nora Hunter; Louise Matthews; James D Foster; Margo E Chase-Topping; Loeske E B Kruuk; Darren J Shaw; Susan M Rhind; Robert G Will; Mark E J Woolhouse

doi:10.1186/1471-2334-6-5

Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies

Suzanne G St Rose, Nora Hunter, Louise Matthews, James D Foster, Margo E Chase-Topping, Loeske E B Kruuk, Darren J Shaw, Susan M Rhind, Robert G Will, Mark E J Woolhouse

Research output: Contribution to journal › Article › peer-review

Abstract

Epidemiological analyses indicate that the age distribution of natural cases of transmissible spongiform encephalopathies (TSEs) reflect age-related risk of infection, however, the underlying mechanisms remain poorly understood. Using a comparative approach, we tested the hypothesis that, there is a significant correlation between risk of infection for scrapie, bovine spongiform encephalopathy (BSE) and variant CJD (vCJD), and the development of lymphoid tissue in the gut.

Original language	English
Pages (from-to)	5
Journal	BMC Infectious Diseases
Volume	6
DOIs	https://doi.org/10.1186/1471-2334-6-5
Publication status	Published - 2006

Access to Document

10.1186/1471-2334-6-5

PDF available here
RoMEO green
Final published version, 512 KB

http://www.biomedcentral.com/1471-2334/6/5

Cite this

@article{a6cbe22b617b4552b73a27c594f4e14f,

title = "Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies",

abstract = "Epidemiological analyses indicate that the age distribution of natural cases of transmissible spongiform encephalopathies (TSEs) reflect age-related risk of infection, however, the underlying mechanisms remain poorly understood. Using a comparative approach, we tested the hypothesis that, there is a significant correlation between risk of infection for scrapie, bovine spongiform encephalopathy (BSE) and variant CJD (vCJD), and the development of lymphoid tissue in the gut.",

author = "\{St Rose\}, \{Suzanne G\} and Nora Hunter and Louise Matthews and Foster, \{James D\} and Chase-Topping, \{Margo E\} and Kruuk, \{Loeske E B\} and Shaw, \{Darren J\} and Rhind, \{Susan M\} and Will, \{Robert G\} and Woolhouse, \{Mark E J\}",

year = "2006",

doi = "10.1186/1471-2334-6-5",

language = "English",

volume = "6",

pages = "5",

journal = "BMC Infectious Diseases",

issn = "1471-2334",

publisher = "BioMed Central",

}

TY - JOUR

T1 - Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies

AU - St Rose, Suzanne G

AU - Hunter, Nora

AU - Matthews, Louise

AU - Foster, James D

AU - Chase-Topping, Margo E

AU - Kruuk, Loeske E B

AU - Shaw, Darren J

AU - Rhind, Susan M

AU - Will, Robert G

AU - Woolhouse, Mark E J

PY - 2006

Y1 - 2006

N2 - Epidemiological analyses indicate that the age distribution of natural cases of transmissible spongiform encephalopathies (TSEs) reflect age-related risk of infection, however, the underlying mechanisms remain poorly understood. Using a comparative approach, we tested the hypothesis that, there is a significant correlation between risk of infection for scrapie, bovine spongiform encephalopathy (BSE) and variant CJD (vCJD), and the development of lymphoid tissue in the gut.

AB - Epidemiological analyses indicate that the age distribution of natural cases of transmissible spongiform encephalopathies (TSEs) reflect age-related risk of infection, however, the underlying mechanisms remain poorly understood. Using a comparative approach, we tested the hypothesis that, there is a significant correlation between risk of infection for scrapie, bovine spongiform encephalopathy (BSE) and variant CJD (vCJD), and the development of lymphoid tissue in the gut.

U2 - 10.1186/1471-2334-6-5

DO - 10.1186/1471-2334-6-5

M3 - Article

C2 - 16405727

SN - 1471-2334

VL - 6

SP - 5

JO - BMC Infectious Diseases

JF - BMC Infectious Diseases

ER -

Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies

Abstract

Access to Document

Fingerprint

Cite this