Comparison between a Mandarin Chinese version of the Childhood Autism Spectrum Test and the Clancy Autism Behaviour Scale in mainland China

Xiang Sun, Carrie Allison, Bonnie Auyeung, Fiona E. Matthews, Zhixiang Zhang, Simon Baron-Cohen, Carol Brayne

Research output: Contribution to journalArticlepeer-review

Abstract

A Mandarin Chinese version of the Childhood Autism Spectrum Test (CAST) and Clancy Autism Behaviour Scale (CABS) were applied to 150 children aged 4–11 years old from clinical settings and mainstream schools in Beijing. All the children were further assessed using the Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview-Revised (ADI-R). The validity of two instruments on screening of ASC was examined and compared using receiver operating characteristic (ROC) curve analysis. The validity of CAST (sensitivity: 89%, specificity: 80%, PPV: 70%) was better than the CABS (sensitivity: 58%, specificity: 84%, PPV: 65%). The area under the curve (AUC) of the CAST (AUC = 0.90) was significantly higher than the CABS (AUC = 0.79, p = 0.0002). The Mandarin CAST demonstrated a better validity in distinguishing children with ASC from children without ASC. It is an acceptable candidate as a screening instrument for ASC in large epidemiological study in Chinese population.
Original languageEnglish
Pages (from-to)1599-1608
Number of pages10
JournalResearch in Developmental Disabilities
Volume35
Issue number7
Early online date25 Apr 2014
DOIs
Publication statusPublished - Jul 2014

Keywords

  • autism
  • screening
  • diagnosis
  • epidemiology
  • CAST
  • CABS
  • China

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