Comparison of dysautonomia across species: Current knowledge and future research opportunities

Callum Atkins*, Caroline Hahn*, Bruce McGorum

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Primary dysautonomia is a complex and often fatal autonomic nervous system disease. This literature review consolidates information on dysautonomia across species. Electronic databases (PubMed, Google Scholar and the Equine Grass Sickness Fund website) were systematically searched for veterinary and human medical literature on the topic. Nine hundred and fifty-six articles were identified, of which 158 were included in this review. The review covers the clinical presentation, etiology, diagnostic approaches, treatment strategies, and prognosis across different species. By integrating findings from multiple species, we aim to enhance understanding and inform future research and medical strategies regarding dysautonomia.

Original languageEnglish
Article numbere70140
Pages (from-to)1-12
Number of pages12
JournalJournal of Veterinary Internal Medicine
Volume39
Issue number4
Early online date17 Jun 2025
DOIs
Publication statusPublished - Jul 2025

Keywords / Materials (for Non-textual outputs)

  • dysautonomia
  • autonomic nervous system
  • grass sickness
  • Key-Gaskell syndrome
  • chromatolysis

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