ComplexViewer: visualisation of curated macromolecular complexes

Colin Combe; Marine Sivade; Henning Hermjakob; Joshua Heimbach; Birgit H M Meldal; Gos Micklem; Sandra Orchard; Juri Rappsilber

doi:10.1093/bioinformatics/btx497

ComplexViewer: visualisation of curated macromolecular complexes

Colin Combe, Marine Sivade, Henning Hermjakob, Joshua Heimbach, Birgit H M Meldal, Gos Micklem, Sandra Orchard, Juri Rappsilber

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex.

Original language	English
Pages (from-to)	3673–3675
Journal	Bioinformatics
Volume	33
Issue number	22
DOIs	https://doi.org/10.1093/bioinformatics/btx497
Publication status	Published - 3 Aug 2017

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Wellcome Centre for Cell Biology
Tollervey, D.
UK-based charities
1/12/16 → 1/12/21
Project: Research
Protein structures in the context of time and space by mass spectrometry
Rappsilber, J.
UK-based charities
1/06/14 → 31/05/21
Project: Research

Juri Rappsilber
- School of Biological Sciences - Personal chair in Proteomics
Person: Academic: Research Active

Cite this

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abstract = "Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex.",

author = "Colin Combe and Marine Sivade and Henning Hermjakob and Joshua Heimbach and Meldal, {Birgit H M} and Gos Micklem and Sandra Orchard and Juri Rappsilber",

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AU - Sivade, Marine

AU - Hermjakob, Henning

AU - Heimbach, Joshua

AU - Meldal, Birgit H M

AU - Micklem, Gos

AU - Orchard, Sandra

AU - Rappsilber, Juri

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AB - Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex.

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ComplexViewer: visualisation of curated macromolecular complexes

Abstract

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Projects

Wellcome Centre for Cell Biology

Protein structures in the context of time and space by mass spectrometry

Profiles

Juri Rappsilber

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