Computational time-of-flight diffuse optical tomography

Ashley Lyons, Francesco Tonolini, Alessandro Boccolini, Audrey Repetti, Robert Henderson, Yves Wiaux, Daniele Faccio

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.
Original languageEnglish
Pages (from-to)575-579
JournalNature Photonics
Early online date20 May 2019
Publication statusPublished - 1 Aug 2019

Keywords / Materials (for Non-textual outputs)

  • imaging and sensing
  • Imaging Techniques
  • single photons and quantum effects
  • ultrafast photonics


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