Computational time-of-flight diffuse optical tomography

Ashley Lyons; Francesco Tonolini; Alessandro Boccolini; Audrey Repetti; Robert Henderson; Yves Wiaux; Daniele Faccio

doi:10.1038/s41566-019-0439-x

Computational time-of-flight diffuse optical tomography

Ashley Lyons, Francesco Tonolini, Alessandro Boccolini, Audrey Repetti, Robert Henderson, Yves Wiaux, Daniele Faccio

School of Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.

Original language	English
Pages (from-to)	575-579
Journal	Nature Photonics
Volume	13
Early online date	20 May 2019
DOIs	https://doi.org/10.1038/s41566-019-0439-x
Publication status	Published - 1 Aug 2019

Keywords / Materials (for Non-textual outputs)

imaging and sensing
Imaging Techniques
single photons and quantum effects
ultrafast photonics

Access to Document

10.1038/s41566-019-0439-x

diffusiveV3_finalAccepted author manuscript, 3.21 MB

https://www.nature.com/articles/s41566-019-0439-x

Ultrafast Imaging using Quantum Technologies (ULTRA-IMAGE)
Henderson, R. (Principal Investigator)
EPSRC
1/02/15 → 31/01/18
Project: Research
UK Quantum Technology Hub in Quantum Enhanced Imaging
Henderson, R. (Principal Investigator)
Other
1/12/14 → 30/11/19
Project: Research

Robert Henderson
- Robert.Hendersoned.acuk
- School of Engineering - Personal Chair of Electronic Imaging
Person: Academic: Research Active

Cite this

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title = "Computational time-of-flight diffuse optical tomography",

abstract = "Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.",

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author = "Ashley Lyons and Francesco Tonolini and Alessandro Boccolini and Audrey Repetti and Robert Henderson and Yves Wiaux and Daniele Faccio",

year = "2019",

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doi = "10.1038/s41566-019-0439-x",

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AU - Lyons, Ashley

AU - Tonolini, Francesco

AU - Boccolini, Alessandro

AU - Repetti, Audrey

AU - Henderson, Robert

AU - Wiaux, Yves

AU - Faccio, Daniele

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.

AB - Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.

KW - imaging and sensing

KW - Imaging Techniques

KW - single photons and quantum effects

KW - ultrafast photonics

U2 - 10.1038/s41566-019-0439-x

DO - 10.1038/s41566-019-0439-x

M3 - Article

SN - 1749-4885

VL - 13

SP - 575

EP - 579

JO - Nature Photonics

JF - Nature Photonics

ER -

Computational time-of-flight diffuse optical tomography

Abstract

Keywords / Materials (for Non-textual outputs)

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Projects

Ultrafast Imaging using Quantum Technologies (ULTRA-IMAGE)

UK Quantum Technology Hub in Quantum Enhanced Imaging

Profiles

Robert Henderson

Cite this