Computer aided assembly and verification of synthetic chromosomes

Giovanni Stracquadanio, Valentin Zulkower

Research output: Chapter in Book/Report/Conference proceedingChapter


Synthetic biology aims at engineering biological systems, ranging from genes to entire genomes. The emerging field of synthetic genomics provides new tools to address questions and tackle challenges in biology and biotechnology impossible to address with current methods. Chromosome scale engineering requires computational tools and workflows to streamline designing, building and verifying long DNA molecules. While a systematic and generic genome design workflow does not exist, here we outline chromosome assembly and verification operations that are at the foundation of every genome scale engineering efforts.
Original languageEnglish
Title of host publicationComputational Methods in Synthetic Biology
Publication statusPublished - 13 Nov 2020

Publication series

NameComputational Methods in Synthetic Biology
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029


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