Conflicting candidates for cattle QTLs

Dirk-Jan de Koning

Research output: Contribution to journalArticlepeer-review

Abstract

Genome scans have identified quantitative trait loci (QTLs) affecting milk yield and composition in dairy cattle. For one QTL on bovine chromosome 6 (BTA6), previously fine-mapped to a 420-Kb region, mutations in two different genes (OPN and ABCG2) have been proposed as the underlying functional mutation. Comparing the arguments for each gene suggests that both mutations are equally probable. However, functional studies and/or additional populations are required to provide a definite answer.
Original languageEnglish
Pages (from-to)301-5
Number of pages5
JournalTrends in Genetics
Volume22
Issue number6
DOIs
Publication statusPublished - Jun 2006

Keywords

  • Animals
  • Cattle
  • Chromosome Mapping
  • Female
  • Lactation
  • Milk
  • Mutation
  • Quantitative Trait Loci

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