Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

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  Innate immunity and endemic diseases in livestock species

  Collie, D. (Principal Investigator), Beard, P. (Co-investigator), Bishop, S. (Co-investigator), Bronsvoort, M. (Co-investigator), Burt, D. (Co-investigator), Fitzgerald, R. (Co-investigator), Freeman, T. (Co-investigator), Gally, D. (Co-investigator), Gill, A. (Co-investigator), Glass, E. (Co-investigator), Hocking, P. (Co-investigator), Hope, J. (Co-investigator), Hume, D. (Co-investigator), Kaiser, P. (Co-investigator), Mabbott, N. (Co-investigator), McLachlan, G. (Co-investigator), Morrison, L. (Co-investigator), Stevens, J. (Co-investigator), Stevens, M. (Co-investigator) & Watson, M. (Co-investigator)

  BBSRC

  1/04/12 → 31/03/17

  Project: Research

  • Macrophage 100%
  • Infectious Agent 64%
  • T Cell 39%
  • Immune Response 32%
  • Gene Expression 31%

• A complete transcriptional map of the human body: systems Biology in toto (Japanese Partnering Grant)

  Hume, D. (Principal Investigator), Freeman, T. (Co-investigator) & Summers, K. (Co-investigator)

  BBSRC

  1/10/11 → 30/09/14

  Project: Research

  • Promoter Region 100%
  • Enhancer Region 76%
  • Transcription 47%
  • MicroRNA 38%
  • Transcription Initiation Site 38%

• Edinburgh clinical academic track(ecat) trasining programme:dr k j baillie

  Hume, D. (Principal Investigator)

  UK-based charities

  1/08/09 → 31/07/12

  Project: Research

  • Enhancer Region 100%
  • Promoter Region 83%
  • Macrophage 75%
  • Influenza 75%
  • TLR4 75%