Conservation of long-range synteny and microsynteny between the genomes of two distantly related nematodes

D B Guiliano, N Hall, S J M Jones, L N Clark, C H Corton, B G Barrell, M L Blaxter, Mark Blaxter

Research output: Contribution to journalArticlepeer-review

Abstract

Comparisons between the genomes of the closely related nematodes Caenorhabditis elegans and Caenorhabditis briggsae reveal high rates of rearrangement, with a bias towards within-chromosome events. To assess whether this pattern is true of nematodes in general, we have used genome sequence to compare two nematode species that last shared a common ancestor approximately 300 million years ago: the model C. elegans and the filarial parasite Brugia malayi.
Original languageEnglish
Pages (from-to)research0057-research0057.14
Number of pages14
JournalGenome Biology
Volume3
Issue number10
DOIs
Publication statusPublished - 2002

Keywords

  • Amino Acid Sequence
  • Animals
  • Brugia malayi
  • Caenorhabditis elegans
  • Caenorhabditis elegans Proteins
  • Chromosome Mapping
  • Conserved Sequence
  • Genes, Helminth
  • Genome
  • Helminth Proteins
  • Molecular Sequence Data
  • Multigene Family
  • Nematoda
  • Sequence Alignment
  • Synteny

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