Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research

James L Alexander; Nicola J Wyatt; Stephane Camuzeaux; Elena Chekmeneva; Beatriz Jimenez; Caroline J Sands; Hannah Fuller; Panteleimon Takis; Tariq Ahmad; Jennifer A Doyle; Ailsa Hart; Peter M Irving; Nicholas A Kennedy; Charlie W Lees; James O Lindsay; Rebecca E McIntyre; Miles Parkes; Natalie J Prescott; Tim Raine; Jack Satsangi; Richard Alexander Speight; Luke Jostins-Dean; Nick Powell; Julian R Marchesi; Christopher J Stewart; Christopher A Lamb

doi:10.1136/gutjnl-2022-329297

Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research

James L Alexander, Nicola J Wyatt, Stephane Camuzeaux, Elena Chekmeneva, Beatriz Jimenez, Caroline J Sands, Hannah Fuller, Panteleimon Takis, Tariq Ahmad, Jennifer A Doyle, Ailsa Hart, Peter M Irving, Nicholas A Kennedy, Charlie W Lees, James O Lindsay, Rebecca E McIntyre, Miles Parkes, Natalie J Prescott, Tim Raine, Jack SatsangiRichard Alexander Speight, Luke Jostins-Dean, Nick Powell, Julian R Marchesi, Christopher J Stewart, Christopher A Lamb

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	379-383
Number of pages	5
Journal	Gut
Volume	73
Issue number	2
DOIs	https://doi.org/10.1136/gutjnl-2022-329297
Publication status	Published - 5 Jan 2024

Keywords / Materials (for Non-textual outputs)

Humans
Metabolome
Metabolomics

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Cite this

Alexander, J. L., Wyatt, N. J., Camuzeaux, S., Chekmeneva, E., Jimenez, B., Sands, C. J., Fuller, H., Takis, P., Ahmad, T., Doyle, J. A., Hart, A., Irving, P. M., Kennedy, N. A., Lees, C. W., Lindsay, J. O., McIntyre, R. E., Parkes, M., Prescott, N. J., Raine, T., ... Lamb, C. A. (2024). Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research. Gut, 73(2), 379-383. https://doi.org/10.1136/gutjnl-2022-329297

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title = "Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research",

keywords = "Humans, Metabolome, Metabolomics",

author = "Alexander, {James L} and Wyatt, {Nicola J} and Stephane Camuzeaux and Elena Chekmeneva and Beatriz Jimenez and Sands, {Caroline J} and Hannah Fuller and Panteleimon Takis and Tariq Ahmad and Doyle, {Jennifer A} and Ailsa Hart and Irving, {Peter M} and Kennedy, {Nicholas A} and Lees, {Charlie W} and Lindsay, {James O} and McIntyre, {Rebecca E} and Miles Parkes and Prescott, {Natalie J} and Tim Raine and Jack Satsangi and Speight, {Richard Alexander} and Luke Jostins-Dean and Nick Powell and Marchesi, {Julian R} and Stewart, {Christopher J} and Lamb, {Christopher A}",

note = "Funding Information: This work is supported by a research grant from The Leona M. and Harry B. Helmsley Charitable Trust (grant #2002-04255). IBD-RESPONSE is supported by the Medical Research Council (grant MR/T032162/1). We are grateful for support from the Newcastle Clinical Trials Unit, the National Phenome Centre, Imperial College London and the NIHR Biomedical Research Centres from Newcastle, Imperial and Cambridge. JLA is the recipient of an NIHR Academic Clinical Lectureship (CL-2019-21-502), funded by Imperial College London and The Joyce and Norman Freed Charitable Trust. NJW is an Academic Clinical Fellow supported by the NIHR. LJD is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 208750/Z/17/Z) and the Kennedy Trust for Rheumatology Research. CJS is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 221745/Z/20/Z) and the 2021 Lister Institute Prize Fellow Award. The views expressed are those of the authors and not necessarily those of our funders, the NIHR or the Department of Health and Social Care. Figure 1A was created with BioRender.com. Funding Information: This study involves human participants. Human samples used in this research project were obtained from the Imperial College Healthcare Tissue Bank (ICHTB). ICHTB is supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London. ICHTB is approved by Wales REC3 to release human material for research (17/WA/0161). Participants gave informed consent to participate in the study before taking part.",

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doi = "10.1136/gutjnl-2022-329297",

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Alexander, JL, Wyatt, NJ, Camuzeaux, S, Chekmeneva, E, Jimenez, B, Sands, CJ, Fuller, H, Takis, P, Ahmad, T, Doyle, JA, Hart, A, Irving, PM, Kennedy, NA, Lees, CW, Lindsay, JO, McIntyre, RE, Parkes, M, Prescott, NJ, Raine, T, Satsangi, J, Speight, RA, Jostins-Dean, L, Powell, N, Marchesi, JR, Stewart, CJ & Lamb, CA 2024, 'Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research', Gut, vol. 73, no. 2, pp. 379-383. https://doi.org/10.1136/gutjnl-2022-329297

TY - JOUR

T1 - Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research

AU - Alexander, James L

AU - Wyatt, Nicola J

AU - Camuzeaux, Stephane

AU - Chekmeneva, Elena

AU - Jimenez, Beatriz

AU - Sands, Caroline J

AU - Fuller, Hannah

AU - Takis, Panteleimon

AU - Ahmad, Tariq

AU - Doyle, Jennifer A

AU - Hart, Ailsa

AU - Irving, Peter M

AU - Kennedy, Nicholas A

AU - Lees, Charlie W

AU - Lindsay, James O

AU - McIntyre, Rebecca E

AU - Parkes, Miles

AU - Prescott, Natalie J

AU - Raine, Tim

AU - Satsangi, Jack

AU - Speight, Richard Alexander

AU - Jostins-Dean, Luke

AU - Powell, Nick

AU - Marchesi, Julian R

AU - Stewart, Christopher J

AU - Lamb, Christopher A

N1 - Funding Information: This work is supported by a research grant from The Leona M. and Harry B. Helmsley Charitable Trust (grant #2002-04255). IBD-RESPONSE is supported by the Medical Research Council (grant MR/T032162/1). We are grateful for support from the Newcastle Clinical Trials Unit, the National Phenome Centre, Imperial College London and the NIHR Biomedical Research Centres from Newcastle, Imperial and Cambridge. JLA is the recipient of an NIHR Academic Clinical Lectureship (CL-2019-21-502), funded by Imperial College London and The Joyce and Norman Freed Charitable Trust. NJW is an Academic Clinical Fellow supported by the NIHR. LJD is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 208750/Z/17/Z) and the Kennedy Trust for Rheumatology Research. CJS is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 221745/Z/20/Z) and the 2021 Lister Institute Prize Fellow Award. The views expressed are those of the authors and not necessarily those of our funders, the NIHR or the Department of Health and Social Care. Figure 1A was created with BioRender.com. Funding Information: This study involves human participants. Human samples used in this research project were obtained from the Imperial College Healthcare Tissue Bank (ICHTB). ICHTB is supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London. ICHTB is approved by Wales REC3 to release human material for research (17/WA/0161). Participants gave informed consent to participate in the study before taking part.

PY - 2024/1/5

Y1 - 2024/1/5

KW - Humans

KW - Metabolome

KW - Metabolomics

U2 - 10.1136/gutjnl-2022-329297

DO - 10.1136/gutjnl-2022-329297

M3 - Article

C2 - 36754608

SN - 0017-5749

VL - 73

SP - 379

EP - 383

JO - Gut

JF - Gut

IS - 2

ER -