CONSTRUCTION OF A 4D ATLAS OF THE DEVELOPING BRAIN USING NON-RIGID REGISTRATION

Ahmed Serag*, Paul Aljabar, Serena Counsell, James Boardman, Jo V. Hajnal, Daniel Rueckert

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper we present an approach for constructing a 4D brain atlas of MR images of preterm baby infants aged between 26-44 weeks of gestation at time of scan. The method used for the creation of an average 4D atlas is based on the use of pair-wise non-rigid registration to eliminate bias in the atlas towards any of the original images. In addition, we use kernel regression to produce age-dependent anatomical templates. The resulting unbiased 4D atlas is much sharper than currently available atlases created using affine registration.

Original languageEnglish
Title of host publication2011 8TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO
Place of PublicationNEW YORK
PublisherInstitute of Electrical and Electronics Engineers
Pages1532-1535
Number of pages4
Publication statusPublished - 2011
Event8th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro - Chicago, Israel
Duration: 30 Mar 20112 Apr 2011

Publication series

NameIEEE International Symposium on Biomedical Imaging
PublisherIEEE
ISSN (Print)1945-7928

Conference

Conference8th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro
Country/TerritoryIsrael
Period30/03/112/04/11

Keywords / Materials (for Non-textual outputs)

  • 4D atlas
  • spatio-temporal
  • neonatal
  • MRI
  • brain development
  • MR-IMAGES
  • GROWTH

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