Controlled adhesion, membrane pinning and vesicle transport by Janus particles

Eleanor J. Ewins*, Koohee Han, Bhuvnesh Bharti, Tom Robinson, Orlin D. Velev, Rumiana Dimova*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The interactions between biomembranes and particles are key to many applications, but the lack of controllable model systems to study them limits the progress in their research. Here, we describe how Janus polystyrene microparticles, half coated with iron, can be partially engulfed by artificial cells, namely giant vesicles, with the goals to control and investigate their adhesion and degree of encapsulation. The interaction between the Janus particles and these model cell membrane systems is mediated by electrostatic charge, offering a further mode of modulation in addition to the iron patches. The ferromagnetic particle coatings also enable manipulation and transport of the vesicles by magnetic fields.

Original languageEnglish
Pages (from-to)3055-3058
Number of pages4
JournalChemical Communications
Volume58
Issue number18
Early online date26 Jan 2022
DOIs
Publication statusPublished - 4 Mar 2022

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