Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

Research output: Contribution to journalArticlepeer-review

Abstract

The ability of a cell to polarize and move is governed by remodeling of the cellular adhesion/cytoskeletal network that is in turn controlled by the Rho family of small GTPases. However, it is not known what signals lie downstream of Rac1 and Cdc42 during peripheral actin and adhesion remodeling that is required for directional migration.
Original languageEnglish
Pages (from-to)1836-46
Number of pages11
JournalCurrent biology : CB
Volume11
Issue number23
Publication statusPublished - 27 Nov 2001

Keywords

  • Biological Transport
  • Cell Adhesion
  • Cell Movement
  • Cell Polarity
  • Focal Adhesion Protein-Tyrosine Kinases
  • Phosphorylation
  • Protein-Tyrosine Kinases
  • rho GTP-Binding Proteins
  • src-Family Kinases

Fingerprint Dive into the research topics of 'Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity'. Together they form a unique fingerprint.

Cite this