Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

Joshua J Smith; Daniel Best; Hon Wai Lam

doi:10.1039/c6cc00603e

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

Joshua J Smith, Daniel Best, Hon Wai Lam

School of Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.

Original language	English
Pages (from-to)	3770-2
Number of pages	3
Journal	Chemical Communications
Volume	52
Issue number	19
Early online date	17 Feb 2016
DOIs	https://doi.org/10.1039/c6cc00603e
Publication status	Published - Mar 2016

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10.1039/c6cc00603e

c6cc00603eFinal published version, 1.64 MB

Increasing the efficiency of chemical synthesis using asymmetric transition metal catalysis
Lam, H.
EPSRC
1/10/10 → 30/09/13
Project: Research

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title = "Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines",

abstract = "Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.",

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N2 - Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.

AB - Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.

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DO - 10.1039/c6cc00603e

M3 - Article

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JO - Chemical Communications

JF - Chemical Communications

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ER -

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

Abstract

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Increasing the efficiency of chemical synthesis using asymmetric transition metal catalysis

Cite this