Correlation of clinical, endocrine and molecular abnormalities with in vivo responses to high-dose testosterone in patients with partial androgen insensitivity syndrome

D G Tincello; P T Saunders; M B Hodgins; N B Simpson; C R Edwards; T B Hargreaves; F C Wu

Correlation of clinical, endocrine and molecular abnormalities with in vivo responses to high-dose testosterone in patients with partial androgen insensitivity syndrome

D G Tincello, P T Saunders, M B Hodgins, N B Simpson, C R Edwards, T B Hargreaves, F C Wu

Deanery of Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

To investigate the responses of two patients previously diagnosed as Reifenstein's syndrome to graded high-dose testosterone in terms of hormone levels, nitrogen balance and sebum secretion and to attempt to correlate these parameters with the properties of their androgen receptors and mutations in the androgen receptor gene.

Original language	English
Pages (from-to)	497-506
Number of pages	10
Journal	Clinical Endocrinology
Volume	46
Issue number	4
Publication status	Published - 1997

Cite this

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title = "Correlation of clinical, endocrine and molecular abnormalities with in vivo responses to high-dose testosterone in patients with partial androgen insensitivity syndrome",

abstract = "To investigate the responses of two patients previously diagnosed as Reifenstein's syndrome to graded high-dose testosterone in terms of hormone levels, nitrogen balance and sebum secretion and to attempt to correlate these parameters with the properties of their androgen receptors and mutations in the androgen receptor gene.",

author = "Tincello, {D G} and Saunders, {P T} and Hodgins, {M B} and Simpson, {N B} and Edwards, {C R} and Hargreaves, {T B} and Wu, {F C}",

year = "1997",

language = "English",

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journal = "Clinical Endocrinology",

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T1 - Correlation of clinical, endocrine and molecular abnormalities with in vivo responses to high-dose testosterone in patients with partial androgen insensitivity syndrome

AU - Tincello, D G

AU - Saunders, P T

AU - Hodgins, M B

AU - Simpson, N B

AU - Edwards, C R

AU - Hargreaves, T B

AU - Wu, F C

PY - 1997

Y1 - 1997

N2 - To investigate the responses of two patients previously diagnosed as Reifenstein's syndrome to graded high-dose testosterone in terms of hormone levels, nitrogen balance and sebum secretion and to attempt to correlate these parameters with the properties of their androgen receptors and mutations in the androgen receptor gene.

AB - To investigate the responses of two patients previously diagnosed as Reifenstein's syndrome to graded high-dose testosterone in terms of hormone levels, nitrogen balance and sebum secretion and to attempt to correlate these parameters with the properties of their androgen receptors and mutations in the androgen receptor gene.

M3 - Article

C2 - 9196614

SN - 0300-0664

VL - 46

SP - 497

EP - 506

JO - Clinical Endocrinology

JF - Clinical Endocrinology

IS - 4

ER -

Correlation of clinical, endocrine and molecular abnormalities with in vivo responses to high-dose testosterone in patients with partial androgen insensitivity syndrome

Abstract / Description of output

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