Creating a Buzz about Macrophages: The Fly as an In Vivo Model for Studying Immune Cell Behavior

Helen Weavers, William Wood

Research output: Contribution to journalArticlepeer-review

Abstract

Drosophila macrophages exhibit functional parallels with their vertebrate counterparts in both their early developmental roles and later diverse roles in health and disease. This, together with the fly's genetic tractability and opportunities for live imaging, has recently established Drosophila as a powerful model to study macrophage behavior in vivo.

Original languageEnglish
Pages (from-to)129-32
Number of pages4
JournalDevelopmental Cell
Volume38
Issue number2
DOIs
Publication statusPublished - 25 Jul 2016

Keywords

  • Animals
  • Drosophila/growth & development
  • Drosophila Proteins/genetics
  • Immunity, Innate/genetics
  • Macrophages/cytology

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