Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2

Immunology and Microbiology

• T Cell Receptor 100%
• T Cell 100%
• Interleukin 2 100%
• Tyrosine 100%
• Antigen Response 9%
• Gene Editing 9%
• Human Cell 9%
• Single Nucleotide Polymorphism 9%
• Clustered Regularly Interspaced Short Palindromic Repeat 9%
• Autoimmune Disease 9%
• Point Mutation 9%
• Allele 9%
• Major Histocompatibility Complex 9%
• Amino Acid 9%
• Tryptophan 9%
• Arginine 9%
• Gain of Function Mutation 9%
• Null Allele 9%
• Genetic Trait 9%
• CD69 9%

Biochemistry, Genetics and Molecular Biology

• T Cell Receptor 100%
• T Cell 100%
• Protein Tyrosine Phosphatase 100%
• Interleukin 2 100%
• Phosphatase 18%
• Amino Acids 9%
• Single-Nucleotide Polymorphism 9%
• Major Histocompatibility Complex 9%
• Genetic Trait 9%
• CD69 9%
• Genome Editing 9%
• Allele 9%
• CRISPR 9%
• Point Mutation 9%
• Gain of Function Mutation 9%
• Tryptophan 9%
• Null Allele 9%
• Arginine 9%