Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2

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• Finished

  Mechanisms and consequences of T cell antigen receptor signalling for normal immune homeostasis and the development of autoimmune disease

  Zamoyska, R.

  UK-based charities

  1/08/17 → 31/07/23

  Project: Research

  • Protein Tyrosine Phosphatase 100%
  • T Cell 100%
  • T Cell Receptor 52%
  • Interleukin 2 52%
  • Tyrosine 50%

• Mechanisms that regulate T cell responses and their failure in autoimmunity

  Zamoyska, R.

  UK-based charities

  1/01/12 → 31/07/17

  Project: Research

  • T Cell 100%
  • T Cell Receptor 78%
  • Cytotoxic T-Cell 72%
  • Tyrosine 52%
  • Protein Tyrosine Phosphatase 48%