Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP

Fernando Siso-Nadal; Jeffrey J Fox; Stéphane A Laporte; Terence E Hébert; Peter S Swain

doi:10.1371/journal.pone.0007189

Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP

Fernando Siso-Nadal, Jeffrey J Fox, Stéphane A Laporte, Terence E Hébert, Peter S Swain

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

To control and manipulate cellular signaling, we need to understand cellular strategies for information transfer, integration, and decision-making. A key feature of signal transduction is the generation of only a few intracellular messengers by many extracellular stimuli.

Original language	English
Article number	e7189
Number of pages	10
Journal	PLoS ONE
Volume	4
Issue number	10
DOIs	https://doi.org/10.1371/journal.pone.0007189
Publication status	Published - 2009

Keywords

Allosteric Site
Animals
Calcium
Cyclic AMP
Humans
Models, Biological
Models, Theoretical
Oscillometry
Protein Kinase C
Signal Transduction

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10.1371/journal.pone.0007189

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Cite this

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AU - Swain, Peter S

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Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP

Abstract

Keywords

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