Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP

Fernando Siso-Nadal, Jeffrey J Fox, Stéphane A Laporte, Terence E Hébert, Peter S Swain

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

To control and manipulate cellular signaling, we need to understand cellular strategies for information transfer, integration, and decision-making. A key feature of signal transduction is the generation of only a few intracellular messengers by many extracellular stimuli.
Original languageEnglish
Article numbere7189
Number of pages10
JournalPLoS ONE
Volume4
Issue number10
DOIs
Publication statusPublished - 2009

Keywords / Materials (for Non-textual outputs)

  • Allosteric Site
  • Animals
  • Calcium
  • Cyclic AMP
  • Humans
  • Models, Biological
  • Models, Theoretical
  • Oscillometry
  • Protein Kinase C
  • Signal Transduction

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