Crystallization of a globular protein in lipid cubic phase

S Tanaka, S U Egelhaaf, Wilson Poon

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the crystallization of a globular protein, lysozyme, in the cubic phase of the lipid mono-olein. The solubility of lysozyme in salt solution decreased by a factor of similar to4 when confined in cubic phase. Monte Carlo simulations and calculations show that this can be explained by the confinement of lysozyme molecules to the narrow water cells in the cubic phase.

Original languageEnglish
Article number128102
Pages (from-to)-
Number of pages4
JournalPhysical Review Letters
Volume92
Issue number12
DOIs
Publication statusPublished - 26 Mar 2004

Keywords

  • LYSOZYME
  • LIQUID
  • NUCLEATION

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