CT and Clinical Predictors of Fatigue at One Month after Stroke

Mansur A Kutlubaev; Susan D Shenkin; Andrew J Farrall; Fiona H Duncan; Susan J Lewis; Carolyn A Greig; Martin S Dennis; Joanna M Wardlaw; Alasdair M J Maclullich; Gillian E Mead

doi:10.1159/000347113

CT and Clinical Predictors of Fatigue at One Month after Stroke

Mansur A Kutlubaev, Susan D Shenkin, Andrew J Farrall, Fiona H Duncan, Susan J Lewis, Carolyn A Greig, Martin S Dennis, Joanna M Wardlaw, Alasdair M J Maclullich, Gillian E Mead

Research output: Contribution to journal › Article › peer-review

Abstract

Fatigue is a common and distressing consequence of stroke, and the aetiology of post-stroke fatigue (PSF) is poorly understood. It is unclear whether chronic brain changes [cerebral atrophy and white matter lesions (WML)], stroke lesion location or certain clinical features are related to its development. The aim of this study was to identify, in patients with acute stroke, whether features in different brain regions on routine CT imaging or routinely collected clinical features predicted PSF at 1 month.

Original language	English
Pages (from-to)	26-34
Number of pages	9
Journal	Cerebrovascular diseases extra
Volume	3
Issue number	1
DOIs	https://doi.org/10.1159/000347113
Publication status	Published - 2013

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10.1159/000347113

CT and Clinical Predictors of Fatigue at One Month after Stroke
This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Final published version, 926 KBLicence: Creative Commons: Attribution Non-Commercial (CC-BY-NC)

http://www.karger.com/Article/FullText/347113

MRC Centre for Cognitive Ageing and Cognitive Epidemiology
Deary, I., Holmes, M., Logie, P., McCulloch, J., Porteous, D., Roberts, N., Seckl, J., Starr, J. & Wardlaw, J.
MRC
1/09/08 → 31/08/13
Project: Research

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title = "CT and Clinical Predictors of Fatigue at One Month after Stroke",

abstract = "Fatigue is a common and distressing consequence of stroke, and the aetiology of post-stroke fatigue (PSF) is poorly understood. It is unclear whether chronic brain changes [cerebral atrophy and white matter lesions (WML)], stroke lesion location or certain clinical features are related to its development. The aim of this study was to identify, in patients with acute stroke, whether features in different brain regions on routine CT imaging or routinely collected clinical features predicted PSF at 1 month.",

author = "Kutlubaev, {Mansur A} and Shenkin, {Susan D} and Farrall, {Andrew J} and Duncan, {Fiona H} and Lewis, {Susan J} and Greig, {Carolyn A} and Dennis, {Martin S} and Wardlaw, {Joanna M} and Maclullich, {Alasdair M J} and Mead, {Gillian E}",

note = "M.A.K. was supported by a European Federation of Neurological Societies{\textquoteright} Scientific Fellowship. The EFAS study was funded by the Chief Scientist Office of the Scottish Government (CZG/2/387). The neuroimaging substudy of the EFAS study was supported by a grant from The University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, part of the cross-council Lifelong Health and Wellbeing Initiative (G0700704/84698). Funding from the BBSRC, EPSRC, ESRC and MRC is gratefully acknowledged.",

year = "2013",

doi = "10.1159/000347113",

language = "English",

volume = "3",

pages = "26--34",

journal = "Cerebrovascular diseases extra",

issn = "1664-5456",

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AU - Kutlubaev, Mansur A

AU - Shenkin, Susan D

AU - Farrall, Andrew J

AU - Duncan, Fiona H

AU - Lewis, Susan J

AU - Greig, Carolyn A

AU - Dennis, Martin S

AU - Wardlaw, Joanna M

AU - Maclullich, Alasdair M J

AU - Mead, Gillian E

N1 - M.A.K. was supported by a European Federation of Neurological Societies’ Scientific Fellowship. The EFAS study was funded by the Chief Scientist Office of the Scottish Government (CZG/2/387). The neuroimaging substudy of the EFAS study was supported by a grant from The University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, part of the cross-council Lifelong Health and Wellbeing Initiative (G0700704/84698). Funding from the BBSRC, EPSRC, ESRC and MRC is gratefully acknowledged.

PY - 2013

Y1 - 2013

N2 - Fatigue is a common and distressing consequence of stroke, and the aetiology of post-stroke fatigue (PSF) is poorly understood. It is unclear whether chronic brain changes [cerebral atrophy and white matter lesions (WML)], stroke lesion location or certain clinical features are related to its development. The aim of this study was to identify, in patients with acute stroke, whether features in different brain regions on routine CT imaging or routinely collected clinical features predicted PSF at 1 month.

AB - Fatigue is a common and distressing consequence of stroke, and the aetiology of post-stroke fatigue (PSF) is poorly understood. It is unclear whether chronic brain changes [cerebral atrophy and white matter lesions (WML)], stroke lesion location or certain clinical features are related to its development. The aim of this study was to identify, in patients with acute stroke, whether features in different brain regions on routine CT imaging or routinely collected clinical features predicted PSF at 1 month.

U2 - 10.1159/000347113

DO - 10.1159/000347113

M3 - Article

C2 - 24052792

VL - 3

SP - 26

EP - 34

JO - Cerebrovascular diseases extra

JF - Cerebrovascular diseases extra

SN - 1664-5456

IS - 1

ER -

CT and Clinical Predictors of Fatigue at One Month after Stroke

Abstract

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MRC Centre for Cognitive Ageing and Cognitive Epidemiology

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