Cyclooxygenase enzyme expression and E series prostaglandin receptor signalling are enhanced in heavy menstruation

O P Milling Smith, H N Jabbour, Hilary Critchley

Research output: Contribution to journalArticlepeer-review

Abstract

Although the mechanisms underlying the causes of heavy menstrual blood loss (MBL) remain to be elucidated, prostaglandins have been previously implicated. This study was initiated to elucidate a pattern of expression of the various components of the cyclooxygenase (COX)-prostaglandin signalling pathways present in the endometrium of women with normal and heavy MBLs.
Original languageEnglish
Pages (from-to)1450-6
Number of pages7
JournalHuman Reproduction
Volume22
Issue number5
DOIs
Publication statusPublished - 2007

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