Cytokine gene polymorphisms and susceptibility to cachexia

Benjamin H L Tan, Kenneth C H Fearon

Research output: Contribution to journalArticlepeer-review


Cachexia is a progressive deterioration of body habitus associated with chronic diseases. The finding that only a proportion of patients with chronic disease develop cachexia has prompted studies looking for genetic polymorphisms that may underlie differential susceptibility. The aim of this review is to explore how inflammation and gene polymorphisms influence susceptibility to cachexia.
Original languageEnglish
Pages (from-to)243-8
Number of pages6
JournalCurrent Opinion in Supportive and Palliative Care
Issue number4
Publication statusPublished - 2010


  • Cachexia
  • Cytokines
  • Genetic Predisposition to Disease
  • Humans
  • Polymorphism, Genetic

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