Cytokine gene polymorphisms and susceptibility to cachexia

Benjamin H L Tan; Kenneth C H Fearon

doi:10.1097/SPC.0b013e32833e4a5d

Cytokine gene polymorphisms and susceptibility to cachexia

Benjamin H L Tan, Kenneth C H Fearon

Deanery of Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Cachexia is a progressive deterioration of body habitus associated with chronic diseases. The finding that only a proportion of patients with chronic disease develop cachexia has prompted studies looking for genetic polymorphisms that may underlie differential susceptibility. The aim of this review is to explore how inflammation and gene polymorphisms influence susceptibility to cachexia.

Original language	English
Pages (from-to)	243-8
Number of pages	6
Journal	Current Opinion in Supportive and Palliative Care
Volume	4
Issue number	4
DOIs	https://doi.org/10.1097/SPC.0b013e32833e4a5d
Publication status	Published - 2010

Keywords / Materials (for Non-textual outputs)

Cachexia
Cytokines
Genetic Predisposition to Disease
Humans
Polymorphism, Genetic

Access to Document

10.1097/SPC.0b013e32833e4a5d

Cite this

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title = "Cytokine gene polymorphisms and susceptibility to cachexia",

abstract = "Cachexia is a progressive deterioration of body habitus associated with chronic diseases. The finding that only a proportion of patients with chronic disease develop cachexia has prompted studies looking for genetic polymorphisms that may underlie differential susceptibility. The aim of this review is to explore how inflammation and gene polymorphisms influence susceptibility to cachexia.",

keywords = "Cachexia, Cytokines, Genetic Predisposition to Disease, Humans, Polymorphism, Genetic",

author = "Tan, {Benjamin H L} and Fearon, {Kenneth C H}",

year = "2010",

doi = "10.1097/SPC.0b013e32833e4a5d",

language = "English",

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T1 - Cytokine gene polymorphisms and susceptibility to cachexia

AU - Tan, Benjamin H L

AU - Fearon, Kenneth C H

PY - 2010

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AB - Cachexia is a progressive deterioration of body habitus associated with chronic diseases. The finding that only a proportion of patients with chronic disease develop cachexia has prompted studies looking for genetic polymorphisms that may underlie differential susceptibility. The aim of this review is to explore how inflammation and gene polymorphisms influence susceptibility to cachexia.

KW - Cachexia

KW - Cytokines

KW - Genetic Predisposition to Disease

KW - Humans

KW - Polymorphism, Genetic

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U2 - 10.1097/SPC.0b013e32833e4a5d

DO - 10.1097/SPC.0b013e32833e4a5d

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SN - 1751-4266

VL - 4

SP - 243

EP - 248

JO - Current Opinion in Supportive and Palliative Care

JF - Current Opinion in Supportive and Palliative Care

IS - 4

ER -

Cytokine gene polymorphisms and susceptibility to cachexia

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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