Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age

Francisca Mutapi; Georgina Winborn; Nicholas Midzi; Matthew Taylor; Takafira Mduluza; Rick M Maizels

doi:10.1186/1471-2334-7-139

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age

Francisca Mutapi, Georgina Winborn, Nicholas Midzi, Matthew Taylor, Takafira Mduluza, Rick M Maizels

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium endemic area and further investigated the relationship between the cytokine responses and infection intensity.

Original language	English
Number of pages	11
Journal	BMC Infectious Diseases
Volume	7
Issue number	139
DOIs	https://doi.org/10.1186/1471-2334-7-139
Publication status	Published - 2007

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title = "Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age",

abstract = "The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium endemic area and further investigated the relationship between the cytokine responses and infection intensity.",

author = "Francisca Mutapi and Georgina Winborn and Nicholas Midzi and Matthew Taylor and Takafira Mduluza and Maizels, {Rick M}",

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AU - Mutapi, Francisca

AU - Winborn, Georgina

AU - Midzi, Nicholas

AU - Taylor, Matthew

AU - Mduluza, Takafira

AU - Maizels, Rick M

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N2 - The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium endemic area and further investigated the relationship between the cytokine responses and infection intensity.

AB - The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium endemic area and further investigated the relationship between the cytokine responses and infection intensity.

U2 - 10.1186/1471-2334-7-139

DO - 10.1186/1471-2334-7-139

M3 - Article

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JO - BMC Infectious Diseases

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SN - 1471-2334

IS - 139

ER -

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age

Abstract

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